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Sol-Gel Derived Hydroxyapatite Coatings for Titanium Implants: A Review.

作者信息

Jaafar Alaa, Hecker Christine, Árki Pál, Joseph Yvonne

机构信息

Institute of Electronics and Sensor Materials, TU Bergakademie Freiberg, 09599 Freiberg, Germany.

出版信息

Bioengineering (Basel). 2020 Oct 14;7(4):127. doi: 10.3390/bioengineering7040127.


DOI:10.3390/bioengineering7040127
PMID:33066421
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7711523/
Abstract

With the growing demands for bone implant therapy, titanium (Ti) and its alloys are considered as appropriate choices for the load-bearing bone implant substitutes. However, the interaction of bare Ti-based implants with the tissues is critical to the success of the implants for long-term stability. Thus, surface modifications of Ti implants with biocompatible hydroxyapatite (HAp) coatings before implantation is important and gained interest. Sol-gel is a potential technique for deposition the biocompatible HAp and has many advantages over other methods. Therefore, this review strives to provide widespread overview on the recent development of sol-gel HAp deposition on Ti. This study shows that sol-gel technique was able to produce uniform and homogenous HAp coatings and identified the role of surface pretreatment of Ti substrate, optimizing the sol-gel parameters, substitution, and reinforcement of HAp on improving the coating properties. Critical factors that influence on the characteristics of the deposited sol-gel HAp films as corrosion resistance, adhesion to substrate, bioactivity, morphological, and structural properties are discussed. The review also highlights the critical issues, the most significant challenges, and the areas requiring further research.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2261/7711523/b186df4f620b/bioengineering-07-00127-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2261/7711523/339ac1f947c1/bioengineering-07-00127-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2261/7711523/f7a601b092e9/bioengineering-07-00127-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2261/7711523/b7a7b303c605/bioengineering-07-00127-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2261/7711523/d1704886c257/bioengineering-07-00127-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2261/7711523/8176612c5120/bioengineering-07-00127-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2261/7711523/4440fda459e3/bioengineering-07-00127-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2261/7711523/a681999bf4df/bioengineering-07-00127-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2261/7711523/b186df4f620b/bioengineering-07-00127-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2261/7711523/339ac1f947c1/bioengineering-07-00127-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2261/7711523/f7a601b092e9/bioengineering-07-00127-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2261/7711523/b7a7b303c605/bioengineering-07-00127-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2261/7711523/d1704886c257/bioengineering-07-00127-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2261/7711523/8176612c5120/bioengineering-07-00127-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2261/7711523/4440fda459e3/bioengineering-07-00127-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2261/7711523/a681999bf4df/bioengineering-07-00127-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2261/7711523/b186df4f620b/bioengineering-07-00127-g008.jpg

相似文献

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Sol-Gel Derived Hydroxyapatite Coatings for Titanium Implants: A Review.

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引用本文的文献

[1]
Effects of different types of modifiers on structural variation of nano-hydroxyapatite for efficient application.

Nanoscale Adv. 2025-6-24

[2]
Comparative Study of Acid Etching and SLA Surface Modification for Titanium Implants.

Materials (Basel). 2025-4-3

[3]
ZnO Nanoparticle-Infused Vaterite Coatings: A Novel Approach for Antimicrobial Titanium Implant Surfaces.

J Funct Biomater. 2025-3-19

[4]
Application of Hydroxyapatite Obtained by Different Techniques: Metabolism and Microarchitecture Characteristics (Review).

Sovrem Tekhnologii Med. 2024

[5]
Advances of Hydroxyapatite Nanoparticles in Dental Implant Applications.

Int Dent J. 2025-6

[6]
Advancements in nanohydroxyapatite: synthesis, biomedical applications and composite developments.

Regen Biomater. 2024-11-5

[7]
Suspension-Sprayed Calcium Phosphate Coatings with Antibacterial Properties.

J Funct Biomater. 2024-9-25

[8]
Natural hydroxyapatite-based nanobiocomposites and their biomaterials-to-cell interaction for bone tissue engineering.

Discov Nano. 2024-10-7

[9]
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Cureus. 2024-9-5

[10]
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Materials (Basel). 2024-6-29

本文引用的文献

[1]
Engineering and functionalization of biomaterials via surface modification.

J Mater Chem B. 2015-3-14

[2]
Substituted hydroxyapatite coatings of bone implants.

J Mater Chem B. 2020-3-4

[3]
Zn-HA/Bi-HA biphasic coatings on Titanium: Fabrication, characterization, antibacterial and biological activity.

Colloids Surf B Biointerfaces. 2020-1-25

[4]
Enhanced cytocompatibility and antibacterial property of zinc phosphate coating on biodegradable zinc materials.

Acta Biomater. 2019-3-29

[5]
Bioactive calcium phosphate materials and applications in bone regeneration.

Biomater Res. 2019-1-14

[6]
Biocompatibility Characteristics of Titanium Coated with Multi Walled Carbon Nanotubes-Hydroxyapatite Nanocomposites.

Materials (Basel). 2019-1-10

[7]
A biocompatible sol-gel derived titania coating for medical implants with antibacterial modification by copper integration.

AMB Express. 2018-2-19

[8]
Bioinspired surface functionalization of metallic biomaterials.

J Mech Behav Biomed Mater. 2017-9-1

[9]
Metallic Biomaterials: Current Challenges and Opportunities.

Materials (Basel). 2017-7-31

[10]
Biocompatibility and Corrosion Protection Behaviour of Hydroxyapatite Sol-Gel-Derived Coatings on Ti6Al4V Alloy.

Materials (Basel). 2017-1-24

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