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咖啡因治疗头痛:有益还是有害?文献简述。

Caffeine for Headaches: Helpful or Harmful? A Brief Review of the Literature.

机构信息

Department of Neurology, Faculty of Medicine and Dentistry, Medical University of Warsaw, 01-809 Warsaw, Poland.

Medical Rehabilitation Facility, The National Institute of Medicine of the Ministry of Interior and Administration, 02-507 Warsaw, Poland.

出版信息

Nutrients. 2023 Jul 17;15(14):3170. doi: 10.3390/nu15143170.

Abstract

Consumption of caffeine in the diet, both daily and occasional, has a significant biological effect on the nervous system. Caffeine, through various and not yet fully investigated mechanisms, affects headaches. This is especially noticeable in migraine. In other headaches such as hypnic headache, post-dural puncture headache and spontaneous intracranial hypotension, caffeine is an important therapeutic agent. In turn, abrupt discontinuation of chronically used caffeine can cause caffeine-withdrawal headache. Caffeine can both relieve and trigger headaches.

摘要

饮食中咖啡因的摄入,无论是日常还是偶尔摄入,都会对神经系统产生显著的生物学影响。咖啡因通过各种尚未完全研究清楚的机制影响头痛。这在偏头痛中尤为明显。在其他头痛,如睡眠性头痛、硬脑膜穿刺后头痛和自发性颅内低血压,咖啡因是一种重要的治疗药物。相反,长期使用咖啡因后突然停药会导致咖啡因戒断性头痛。咖啡因既可以缓解也可以引发头痛。

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本文引用的文献

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Curr Opin Neurol. 2022 Jun 1;35(3):360-366. doi: 10.1097/WCO.0000000000001065.
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Spontaneous Intracranial Hypotension.自发性颅内低压
N Engl J Med. 2021 Dec 2;385(23):2173-2178. doi: 10.1056/NEJMra2101561.
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Dehydration and Headache.脱水和头痛。
Curr Pain Headache Rep. 2021 Jul 15;25(8):56. doi: 10.1007/s11916-021-00966-z.

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