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咖啡因作为术后加速康复途径的一部分:对证据和知识空白的叙述性综述。

Caffeine supplementation as part of enhanced recovery after surgery pathways: a narrative review of the evidence and knowledge gaps.

机构信息

Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.

出版信息

Can J Anaesth. 2021 Jun;68(6):876-879. doi: 10.1007/s12630-021-01943-1. Epub 2021 Feb 9.

DOI:10.1007/s12630-021-01943-1
PMID:33564991
Abstract

Caffeine is used daily by 85% of United States adults and caffeine withdrawal is a major cause of perioperative headache. Studies have shown that caffeine supplementation in chronic caffeinators reduces the incidence of perioperative headache. This narrative review discusses the perioperative implications of caffeine withdrawal and outlines the benefits of and strategies of caffeine supplementation in the perioperative period. It is time to "wake up and smell the coffee" on integration of caffeine into established enhanced recovery after surgery protocols as a mechanism to consistently provide perioperative caffeine replacement.

摘要

85%的美国成年人每天都在摄入咖啡因,咖啡因戒断是围手术期头痛的主要原因。研究表明,慢性咖啡因使用者补充咖啡因可降低围手术期头痛的发生率。本综述讨论了咖啡因戒断的围手术期影响,并概述了围手术期补充咖啡因的益处和策略。现在是时候将咖啡因纳入既定的术后加速康复方案中,作为一种持续提供围手术期咖啡因替代的机制,“认识到咖啡因的重要性”了。

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Effect of Caffeine Intake on Postoperative Ileus: A Systematic Review and Meta-Analysis.咖啡因摄入对术后肠梗阻的影响:系统评价和荟萃分析。
Dig Surg. 2020;37(1):22-31. doi: 10.1159/000496431. Epub 2019 Jan 11.
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Higher habitual dietary caffeine consumption is related to lower experimental pain sensitivity in a community-based sample.习惯性较高的膳食咖啡因摄入量与基于社区的样本中较低的实验性疼痛敏感性有关。
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Caffeine Accelerates Emergence from Isoflurane Anesthesia in Humans: A Randomized, Double-blind, Crossover Study.咖啡因可加快异氟醚麻醉患者苏醒:一项随机、双盲、交叉研究。
Anesthesiology. 2018 Nov;129(5):912-920. doi: 10.1097/ALN.0000000000002367.
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