Karachaliou Marianna, Damianaki Irene, Moudatsaki Maria, Margetaki Katerina, Roumeliotaki Theano, Bempi Vicky, Moudatsaki Marina, Chatzi Lida Vaia, Vafeiadi Marina, Kogevinas Manolis
Barcelona Institute for Global Health, 08036 Barcelona, Spain.
5th Local Healthcare Unit, 71307 Heraklion, Greece.
Vaccines (Basel). 2023 Jul 14;11(7):1241. doi: 10.3390/vaccines11071241.
In Greece, influenza vaccination is currently recommended for children with high-risk conditions. There are limited data on influenza vaccination uptake among Greek children with and without high-risk conditions. We aim to describe the annual influenza vaccination uptake until the age of ten in a population-based mother-child cohort and identify the factors influencing vaccination rates.
Immunization data from the child's health cards at 4 and 10 years were available for 830 and 298 children participating in the Rhea cohort (2008-2019). We calculated vaccination coverage by age, winter season and among children with asthma and obesity for whom the vaccine is indicated. Univariable and multivariable stepwise logistic regression models were utilized to identify the association between several sociodemographic, lifestyle and health-related variables and vaccine uptake by age four.
By the ages of four and ten, 37% and 40% of the children, respectively, had received at least one influenza vaccination. Only 2% of the children were vaccinated for all winter seasons during their first four years of life. The vaccination rate was highest at the age of two and during the 2009-2010 season. Vaccination rates for children with asthma and obesity were 18.2% and 13.3% at age four and 8.3% and 2.9% at age ten. About 10% of all vaccines were administered after December and 24% of the children received only one dose upon initial vaccination. Children with younger siblings and those who had experienced more respiratory infections were more likely to be vaccinated by the age of four, while children exposed to smoking were less likely to be vaccinated.
Children in our study were more likely to be vaccinated against influenza at an early age with the peak occurring at the age of two. Nonetheless, annual vaccination uptake was uncommon. Vaccination rates of children with asthma and obesity were well below the national target of 75% for individuals with chronic conditions. Certain groups may merit increased attention in future vaccination campaigns such as children raised in families with unfavourable health behaviours.
在希腊，目前建议对有高危状况的儿童接种流感疫苗。关于希腊有和没有高危状况的儿童流感疫苗接种率的数据有限。我们旨在描述一个基于人群的母婴队列中10岁以下儿童的年度流感疫苗接种率，并确定影响接种率的因素。
参与瑞亚队列研究（2008 - 2019年）的830名4岁儿童和298名10岁儿童的儿童健康卡免疫数据可用。我们按年龄、冬季以及有哮喘和肥胖且有疫苗接种指征的儿童计算了疫苗接种覆盖率。采用单变量和多变量逐步逻辑回归模型来确定几个社会人口统计学、生活方式和健康相关变量与4岁时疫苗接种之间的关联。
到4岁和10岁时，分别有37%和40%的儿童至少接种过一次流感疫苗。在生命的头四年中，只有2%的儿童在所有冬季都接种了疫苗。接种率在2岁时和2009 - 2010年季节最高。4岁时哮喘儿童和肥胖儿童的接种率分别为18.2%和13.3%，10岁时分别为8.3%和2.9%。所有疫苗中约10%在12月之后接种，24%的儿童在初次接种时仅接种了一剂。有年幼兄弟姐妹的儿童以及经历过更多呼吸道感染的儿童在4岁时更有可能接种疫苗，而接触过吸烟环境的儿童接种疫苗的可能性较小。
我们研究中的儿童在幼年时更有可能接种流感疫苗，接种高峰出现在2岁。尽管如此，年度接种率并不常见。哮喘儿童和肥胖儿童的接种率远低于慢性病患者75%的国家目标。在未来的疫苗接种活动中，某些群体可能值得更多关注，例如在健康行为不良的家庭中成长的儿童。
