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西班牙蒙古族人群乙型肝炎、丙型肝炎和丁型肝炎的社区筛查和治疗衔接策略。

Community Strategy for Hepatitis B, C, and D Screening and Linkage to Care in Mongolians Living in Spain.

机构信息

Departamento de Hepatología, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain.

Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas, 28029 Madrid, Spain.

出版信息

Viruses. 2023 Jul 5;15(7):1506. doi: 10.3390/v15071506.

Abstract

Mongolia has one of the highest viral hepatitis infection (B, C, and D) rates in the world. The aims of this study were to increase awareness of this disease and promote viral hepatitis screening in the Mongolian community living in Spain. Through a native community worker, Mongolian adults were invited to a community program consisting of an educational activity, an epidemiological questionnaire, and rapid point-of-care testing for hepatitis B and C. In those testing positive, blood extraction was performed to determine serological and virological parameters. In total, 280 Mongolians were invited to the program and 222 (79%) attended the event: 139 were women (63%), mean age was 42 years, and 78 (35%) had viral hepatitis risk factors. Testing found 13 (5.8%) anti-HCV-positive individuals, 1 with detectable HCV RNA (0.5%), 8 HBsAg-positive (3.6%), and 7 with detectable HBV DNA (3.1%). One additional individual had HBV/HCV co-infection with detectable HBV DNA and HCV RNA. Two subjects had hepatitis B/D co-infection (0.9%). The knowledge questionnaire showed a 1.64/8-point (20.5%) increase in correct answers after the educational activity. In summary, a viral hepatitis community program was feasible and widely accepted. It increased awareness of this condition in the Mongolian community in Spain and led to linkage to care in 22 participants, 50% of whom were unaware of their infection.

摘要

蒙古的病毒性肝炎感染(B、C 和 D 型)率位居世界前列。本研究旨在提高对该病的认识,并在居住在西班牙的蒙古人群中推广病毒性肝炎筛查。通过一名当地社区工作者,邀请蒙古成年人参加社区项目,该项目包括教育活动、流行病学问卷调查和乙型和丙型肝炎即时检测。在检测呈阳性的人中,进行血液提取以确定血清学和病毒学参数。共有 280 名蒙古人受邀参加该项目,222 人(79%)参加了活动:139 人为女性(63%),平均年龄为 42 岁,78 人(35%)有病毒性肝炎风险因素。检测发现 13 名(5.8%)抗 HCV 阳性个体,1 名 HCV RNA 可检测(0.5%),8 名 HBsAg 阳性(3.6%),7 名 HBV DNA 可检测(3.1%)。另有 1 名个体同时感染 HBV 和 HCV,HBV DNA 和 HCV RNA 均可检测。2 名个体同时感染乙型肝炎和丙型肝炎(0.9%)。知识问卷显示,在教育活动后,正确答案增加了 1.64/8 分(20.5%)。总之,病毒性肝炎社区项目是可行的,且被广泛接受。该项目提高了西班牙蒙古社区对该病的认识,并促使 22 名参与者(50%的参与者此前并不知道自己已感染)联系到医护人员。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ea1/10384786/4741cdc7464a/viruses-15-01506-g001.jpg

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