Boulloche J, Mallet E, Basuyau J P, Tayot P, Samson-Dollfus D
Acta Paediatr Scand. 1986 Jul;75(4):530-3. doi: 10.1111/j.1651-2227.1986.tb10244.x.
Global serum levels of IgE (PRIST, Phadebas) and specific anti-cow's milk IgE (RAST) were measured in populations of infants with a history of one or more episodes of milk aspiration (n = 12), victims of the sudden infant death syndrome (SIDS) (n = 18), "near miss" SIDS infants (n = 23), siblings of a SIDS victim ((n = 21) and control infants (n = 38). Only the infants with a past history of milk aspiration had significantly raised global and specific IgE. The absence of raised specific IgE in the subjects who died from SIDS argues against the hypothesis of sensitisation to cow's milk proteins during a previous episode of aspiration. Nasopharyngeal reflux is frequently seen in near-miss infants. This reflux is more often responsible for reflex apnoea due to stimulation of the laryngeal chemo-receptors than to a fatal aspiration.
对有一次或多次乳汁误吸史的婴儿群体（n = 12）、婴儿猝死综合征（SIDS）受害者（n = 18）、“近 misses” SIDS婴儿（n = 23）、SIDS受害者的兄弟姐妹（n = 21）以及对照婴儿（n = 38）测量了血清总IgE水平（PRIST法、Phadebas法）和特异性抗牛奶IgE水平（RAST法）。只有有乳汁误吸既往史的婴儿血清总IgE和特异性IgE显著升高。死于SIDS的受试者中特异性IgE未升高，这与先前误吸发作期间对牛奶蛋白致敏的假说相悖。近 misses婴儿中经常可见鼻咽反流。这种反流更常因刺激喉化学感受器导致反射性呼吸暂停，而非致命性误吸。
