Department of Anesthesiology, People's Hospital of China Medical University (People's Hospital of Liaoning Province), No. 33 Wenyi Road, Shenyang, 110016, China.
Department of Anesthesiology, Jinqiu Hospital of Liaoning Province, No. 317 Xiaonan Street, Shenyang, 110016, China.
J Anesth. 2023 Oct;37(5):734-740. doi: 10.1007/s00540-023-03225-0. Epub 2023 Jul 29.
Music intervention is commonly used as a non-pharmacologic therapeutic modality to alleviate anxiety in perioperative patients. This study aimed to assess the sedative and anxiolytic effects of music on elderly patients receiving transurethral resection of prostate (TURP) under spinal anesthesia.
This was a prospective randomized controlled trial on patients who aged over 60 and received TURP under spinal anesthesia. Participants were randomized to the music group or the control group (no music). The primary outcome was perioperative BIS values, and the secondary outcomes were patient's perioperative anxiety levels, heart rate (HR), blood pressure, and patient satisfaction score.
A total of 82 patients were analyzed. The perioperative BIS values in the music group were significantly lower than those of the control group at almost all time points (P < 0.001), as well as showed a significant reduction compared with baseline (P < 0.001), whereas the control group did not. In comparison with the control group, systolic blood pressure (SBP) significantly decreased in the music group at the beginning (mean difference, - 8.0 mmHg; 95% CI - 15.70 to 0.35; P = 0.041) and the 60th minute (mean difference, - 7.9 mmHg; 95% CI - 15.30 to 0.51; P = 0.037) of TURP. Furthermore, compared with baseline within the music group, diastolic blood pressure (DBP) and HR significant reduced at whole time points (P < 0.05), yet the control group not.
Music intervention effectively provided slight sedation for elderly patients when undergoing TURP under spinal anesthesia without sedatives.
音乐干预通常被用作缓解围手术期患者焦虑的非药物治疗方法。本研究旨在评估音乐对接受脊髓麻醉下经尿道前列腺切除术（TURP）的老年患者的镇静和抗焦虑作用。
这是一项针对 60 岁以上并接受脊髓麻醉下 TURP 的患者的前瞻性随机对照试验。参与者被随机分为音乐组或对照组（无音乐）。主要结局是围手术期 BIS 值，次要结局是患者围手术期焦虑水平、心率（HR）、血压和患者满意度评分。
共分析了 82 例患者。音乐组的围手术期 BIS 值在几乎所有时间点均明显低于对照组（P<0.001），与基线相比也明显降低（P<0.001），而对照组则没有。与对照组相比，音乐组在 TURP 开始时（平均差异，-8.0mmHg；95%置信区间-15.70 至 0.35；P=0.041）和第 60 分钟时（平均差异，-7.9mmHg；95%置信区间-15.30 至 0.51；P=0.037）的收缩压（SBP）显著降低。此外，与音乐组内的基线相比，舒张压（DBP）和 HR 在整个时间点均显著降低（P<0.05），而对照组则没有。
在没有镇静剂的情况下，音乐干预可有效为接受脊髓麻醉下 TURP 的老年患者提供轻度镇静。
