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在一家三级转诊医院接受手术治疗胆总管结石的短期和长期结果。

The short- and long-term outcome after the surgical management of common bile duct stones in a tertiary referral hospital.

机构信息

Clarunis, University Centre for Gastrointestinal and Liver Diseases, 4002, Basel, Switzerland.

Faculty of Medicine, University of Basel, Klingelbergstrasse 61, 4056, Basel, Switzerland.

出版信息

Langenbecks Arch Surg. 2023 Jul 29;408(1):288. doi: 10.1007/s00423-023-03011-2.

DOI:10.1007/s00423-023-03011-2
PMID:37515739
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10386922/
Abstract

BACKGROUND

The removal of common bile duct stones by endoscopic retrograde cholangiopancreatography (ERCP) shows excellent results with low complication rates and is therefore considered a gold standard. However, in case of stones non-removable by ERCP, surgical extraction is needed. The surgical approach is still controversial and clinical guidelines are missing. This study aims to analyze the outcomes of patients treated with choledochotomy or hepaticojejunostomy for common bile duct stones.

METHODS

All patients who underwent choledochotomy or hepaticojejunostomy for common bile duct stones at a tertiary referral hospital over 11 years were included. The analyzed data contains basic demographics, diagnostics, surgical parameters, length of hospitalization, and morbidity and mortality.

RESULTS

Over the study period, 4375 patients underwent cholecystectomy, and 655 received an ERCP with stone extraction, with 48 of these patients receiving subsequent surgical treatment. ERCP was attempted in 23/30 (77%) of the choledochotomy patients pre/intraoperatively and 11/18 (56%) in hepaticojejunostomy patients. The 30-day major complication rate (Clavien-Dindo > II) was 1/30 (3%) in the choledochotomy group and 2/18 (11%) in the hepaticojejunostomy group. Complications after 30 days occurred in 3/30 (10%) patients and 2/18 (11%), respectively, and no mortality occurred.

CONCLUSION

ERCP should still be considered the gold standard, although due to low short- and long-term morbidity rates, choledochotomy and hepaticojejunostomy represent effective surgical solutions for common bile duct stones.

摘要

背景

经内镜逆行胰胆管造影术(ERCP)取除胆总管结石具有并发症发生率低、效果极好的特点,因此被视为金标准。然而,对于无法通过 ERCP 取除的结石,则需要进行外科手术。目前,外科手术方法仍存在争议,且缺乏临床指南。本研究旨在分析通过胆总管切开术或胆肠吻合术治疗胆总管结石的患者结局。

方法

本研究纳入了 11 年间在一家三级转诊医院接受胆总管切开术或胆肠吻合术治疗胆总管结石的所有患者。分析的数据包括基本人口统计学、诊断、手术参数、住院时间以及发病率和死亡率。

结果

研究期间,共有 4375 例患者接受了胆囊切除术,655 例患者接受了 ERCP 取石术,其中 48 例患者随后接受了外科治疗。在胆总管切开术患者中,有 23/30(77%)例患者在术前/术中尝试了 ERCP,而在胆肠吻合术患者中,有 11/18(56%)例患者尝试了 ERCP。胆总管切开术组的 30 天主要并发症发生率(Clavien-Dindo>Ⅱ级)为 1/30(3%),胆肠吻合术组为 2/18(11%)。术后 30 天发生的并发症分别为 3/30(10%)例和 2/18(11%)例,均无死亡病例。

结论

尽管胆总管切开术和胆肠吻合术具有较低的短期和长期并发症发生率,但 ERCP 仍应被视为金标准。