Blomstrand E, Kaijser L, Martinsson A, Bergh U, Ekblom B
Acta Physiol Scand. 1986 Aug;127(4):477-84. doi: 10.1111/j.1748-1716.1986.tb07931.x.
Seven male subjects performed intensive cycle exercise to exhaustion at subnormal muscle temperature (Tm, 29 +/- 2.8 degrees C). Exercise at exactly the same rate of exercise and duration (370 +/- 34 W, 1.5 +/- 0.15 min) was then repeated with normal Tm (35 +/- 0.9 degrees C). During exercise both the arterial (a) and femoral venous (fv) contents of oxygen were significantly higher at subnormal than at normal Tm, because of the higher haemoglobin concentration, but the a-fv oxygen difference was the same in the two situations. The rate of increase in lactate concentration in both arterial and venous blood during exercise was the same in two situations. During exercise the plasma concentrations of adrenaline and noradrenaline in arterial and venous blood were significantly higher at subnormal than at normal Tm. At rest and after exercise the calf blood flow was significantly reduced at subnormal Tm. At the end of exercise the concentrations of glucose-6-phosphate and lactate in the muscle were significantly higher at subnormal Tm than in the muscle of normal temperature. These findings suggest that there was a greater increase in glycolysis in the muscle of subnormal temperature during exercise, possibly as a result of impaired work efficiency and/or reduced blood flow in the cold muscle.
七名男性受试者在低于正常的肌肉温度（Tm，29±2.8摄氏度）下进行高强度自行车运动直至力竭。然后在正常肌肉温度（35±0.9摄氏度）下，以完全相同的运动速率和持续时间（370±34瓦，1.5±0.15分钟）重复运动。运动期间，由于血红蛋白浓度较高，低于正常温度时动脉（a）和股静脉（fv）的氧含量均显著高于正常温度时，但两种情况下a-fv氧差相同。两种情况下运动期间动脉血和静脉血中乳酸浓度的增加速率相同。运动期间，低于正常温度时动脉血和静脉血中肾上腺素和去甲肾上腺素的血浆浓度显著高于正常温度时。在休息时和运动后，低于正常温度时小腿血流量显著减少。运动结束时，低于正常温度时肌肉中葡萄糖-6-磷酸和乳酸的浓度显著高于正常温度时的肌肉。这些发现表明，运动期间低于正常温度的肌肉中糖酵解增加幅度更大，这可能是由于工作效率受损和/或冷肌肉中血流量减少所致。
