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脑微出血。磁敏感加权成像序列的应用价值。

Cerebral microbleeds. Utility of SWI sequences.

作者信息

Martínez Camblor L, Peña Suárez J M, Martínez-Cachero García M, Santamarta Liébana E, Rodríguez Castro J, Saiz Ayala A

机构信息

Servicio de Radiodiagnóstico, Hospital Universitario Central de Asturias, Oviedo, Spain.

Servicio de Radiodiagnóstico, Hospital Universitario Central de Asturias, Oviedo, Spain.

出版信息

Radiologia (Engl Ed). 2023 Jul-Aug;65(4):362-375. doi: 10.1016/j.rxeng.2022.12.006. Epub 2023 Jul 3.

Abstract

OBJECTIVES

Define the concept of cerebral microbleeds (CMBs) and describe the most useful MRI sequences for detecting this finding. Review the entities that most frequently present with CMBs and that may benefit from the use of susceptibility-weighted imaging (SWI) sequences.

CONCLUSIONS

SWI is a useful MRI sequence for the detection and characterization of microhemorrhages, venous structures and other sources of susceptibility in imaging. SWI is particularly sensitive to local magnetic field inhomogeneities generated by certain substances and is superior to T2* GRE sequences for this assessment. CMBs may be seen in different neurologic conditions, in certain infrequent clinical contexts and have a key role as a biomarker status in gliomas (ITTS) and as a marker of inflammatory activity in multiple sclerosis.

摘要

目的

定义脑微出血(CMBs)的概念,并描述用于检测这一发现的最有用的MRI序列。回顾最常出现CMBs且可能受益于使用磁敏感加权成像(SWI)序列的疾病。

结论

SWI是一种用于检测和表征微出血、静脉结构及成像中其他磁敏感源的有用MRI序列。SWI对某些物质产生的局部磁场不均匀性特别敏感,在该评估方面优于T2*梯度回波序列。CMBs可见于不同的神经系统疾病、某些罕见的临床情况,并且在胶质瘤(ITTS)中作为生物标志物状态以及在多发性硬化中作为炎症活动的标志物发挥关键作用。

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