Campbell University School of Osteopathic Medicine, Lillington, NC, USA.
Duke University School of Medicine, Durham, NC, USA.
Foot Ankle Surg. 2023 Dec;29(8):551-559. doi: 10.1016/j.fas.2023.07.010. Epub 2023 Jul 26.
Platelet-rich plasma (PRP) is an autologous serum containing higher concentrations of platelets and growth factors above normal blood. The process of obtaining PRP involves the extraction of blood from the patient which is then centrifuged to obtain a concentrated suspension of platelets. PRP continues to evolve as a potential treatment modality with many applications in orthopaedic surgery. The therapeutic components of PRP possess numerous theoretical regenerative properties. The present manuscript outlines how PRP is prepared, noting the tremendous variability between preparation protocols. Given the growing body of evidence examining the use of PRP in pathologies of the foot and ankle, we assess its efficacy as it relates to our field. Specifically, we evaluate the literature in the past five years regarding the role of PRP in treating plantar fasciitis, Achilles tendinopathy, insertional Achilles tendinitis, Achilles tendon ruptures, osteochondral lesions of the talus, hallux rigidus, and ankle osteoarthritis.
富血小板血浆（PRP）是一种自体血清，其中含有高于正常血液的血小板和生长因子。获得 PRP 的过程涉及从患者中提取血液，然后将其离心以获得血小板的浓缩悬浮液。PRP 作为一种潜在的治疗方式不断发展，在骨科手术中有许多应用。PRP 的治疗成分具有许多理论上的再生特性。本文概述了 PRP 的制备方法，并指出了制备方案之间的巨大差异。鉴于越来越多的证据研究 PRP 在足部和踝关节疾病中的应用，我们评估了其在我们领域中的疗效。具体来说，我们评估了过去五年中关于 PRP 在治疗足底筋膜炎、跟腱病、插入性跟腱炎、跟腱断裂、距骨骨软骨病变、踇僵硬和踝关节骨关节炎中的作用的文献。
