Shah P K, Maddahi J, Staniloff H M, Ellrodt A G, Pichler M, Swan H J, Berman D S
Am J Cardiol. 1986 Sep 1;58(6):387-93. doi: 10.1016/0002-9149(86)90001-9.
To determine the spectrum and prognostic implications of left and right ventricular (LV and RV) ejection fractions (EFs) in acute myocardial infarction (AMI), radionuclide ventriculography was performed in 114 consecutive patients, admitted without (Killip class I, 78 patients) or with (killip class II, 36 patients) clinical signs of pulmonary congestion within 24 hours of onset of symptoms of a transmural AMI. Mean LVEF was significantly lower in patients in Killip class II than in those in class I (0.32 +/- 0.11 vs 0.46 +/- 0.15, p less than 0.001) and in patients with anterior than inferior AMI (0.34 +/- 0.11 vs 0.52 +/- 0.14, p less than 0.001). Of the 36 patients with a severely depressed (0.30 or less) LVEF, 15 (42%) were in Killip class I. Mean RVEF did not differ significantly between Killip class I and II patients (0.42 +/- 0.11 vs 0.40 +/- 0.12, difference not significant) but was significantly lower in patients with inferior than anterior AMI (0.38 +/- 0.09 vs 0.44 +/- 0.11, p = 0.005). In patients with inferior AMI, a depressed RVEF (0.38 or less) was associated with a normal LVEF in 30% and a depressed LVEF in 20%, whereas in those with anterior AMI, a depressed RVEF, observed in 25% of patients, occurred only in association with a depressed LVEF.(ABSTRACT TRUNCATED AT 250 WORDS)
为了确定急性心肌梗死（AMI）患者左、右心室射血分数（EF）的范围及其预后意义，对114例连续入院的患者进行了放射性核素心室造影检查。这些患者在透壁性AMI症状发作后24小时内入院，其中无肺部充血临床体征的（Killip I级，78例）或有肺部充血临床体征的（Killip II级，36例）。Killip II级患者的平均左心室射血分数（LVEF）显著低于Killip I级患者（分别为0.32±0.11和0.46±0.15，p<0.001），前壁AMI患者的LVEF也显著低于下壁AMI患者（分别为0.34±0.11和0.52±0.14，p<0.001）。在36例LVEF严重降低（≤0.30）的患者中，15例（42%）为Killip I级。Killip I级和II级患者的平均右心室射血分数（RVEF）无显著差异（分别为0.42±0.11和0.40±0.12，差异不显著），但下壁AMI患者的RVEF显著低于前壁AMI患者（分别为0.38±0.09和0.44±0.11，p = 0.005）。在下壁AMI患者中，30%的患者RVEF降低（≤0.38）时LVEF正常，20%的患者LVEF降低；而在前壁AMI患者中，25%的患者出现RVEF降低，且均伴有LVEF降低。（摘要截取自250字）
