Basawa Renuka, Kabra Suhani, Khile Dnyanada Anil, Faruk Abbu Rahil Ummar, Parekkadan Serin Joby, Thomas Naomi Ann, Kim Se Kwon, Raval Ritu
Department of Biotechnology, Manipal Institute of Technology (MIT), Manipal Academy of Higher Education (MAHE), Manipal 576104, Karnataka, India.
Manipal Biomachines, Manipal Institute of Technology (MIT), Manipal Academy of Higher Education (MAHE), Manipal 576104, Karnataka, India.
Heliyon. 2023 Jul 13;9(7):e18197. doi: 10.1016/j.heliyon.2023.e18197. eCollection 2023 Jul.
The pisciculture industry has grown multi-fold over the past few decades. However, a surge in development and nutrient demand has led to the establishment of numerous challenges. Being a potential solution, chitosan has gained attention as a bio nanocomposite for its well-acclaimed properties including biodegradability, non-toxicity, immunomodulatory effects, antimicrobial activity, and biocompatibility. This biopolymer and its derivatives can be transformed into various structures, like micro and nanoparticles, for various purposes. Consequently, with regards to these properties chitin and its derivatives extend their application into drug delivery, food supplementation, vaccination, and preservation. This review focuses on the clinical advancements made in fish biotechnology via chitosan and its derivatives and highlights its prospective expansion into the pisciculture industry-in particular, warm-water species.
在过去几十年里，水产养殖业实现了数倍增长。然而，发展和营养需求的激增带来了诸多挑战。壳聚糖作为一种潜在的解决方案，因其具有广受赞誉的特性，如生物可降解性、无毒性、免疫调节作用、抗菌活性和生物相容性，而作为一种生物纳米复合材料受到关注。这种生物聚合物及其衍生物可以转化为各种结构，如微米和纳米颗粒，以用于各种目的。因此，鉴于这些特性，甲壳素及其衍生物在药物递送、食品补充、疫苗接种和保存等方面得到了广泛应用。本综述重点关注壳聚糖及其衍生物在鱼类生物技术方面取得的临床进展，并强调其在水产养殖业，特别是温水鱼类养殖业中的潜在扩展应用。
