Kanoh T
Am J Clin Pathol. 1986 Sep;86(3):363-5. doi: 10.1093/ajcp/86.3.363.
The present investigation was undertaken in order to elucidate the delayed reaction of Bence Jones proteins to sulfosalicylic acid. The author observed this interesting phenomenon in 2 of 32 untreated patients with multiple myeloma who excreted Bence Jones proteins. Their urine samples contained a large amount of Bence Jones proteins with alpha 2 mobility on electrophoresis, which is rarely encountered in urinary Bence Jones proteins. The delayed reaction may be linked, in part at least, to the chemical properties of Bence Jones proteins responsible for alpha 2 mobility.
进行本研究是为了阐明本-周蛋白对磺基水杨酸的延迟反应。作者在32例未治疗的多发性骨髓瘤患者中有2例观察到了这种有趣的现象，这2例患者排泄本-周蛋白。他们的尿液样本含有大量在电泳中具有α2迁移率的本-周蛋白，这在尿本-周蛋白中很少见。这种延迟反应可能至少部分与导致α2迁移率的本-周蛋白的化学性质有关。
