Alharbi Ahmad M
Department of Clinical Laboratories Sciences, College of Applied Medical Sciences, Taif University, Taif 21944, Saudi Arabia.
Saudi J Biol Sci. 2023 Sep;30(9):103739. doi: 10.1016/j.sjbs.2023.103739. Epub 2023 Jul 13.
Mortality due to infectious diseases continues to rise globally, despite advances in antimicrobial therapy and supportive care. This is evident with the occurrence of coronavirus disease 2019 (COVID-19) pandemic, instigated by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Saudi Arabia, an eminent country within the Arab region, has had significant impact during global pandemics, concomitant with the fact that millions of Muslims travel to Saudi Arabia for pilgrimages every year. Herein, we discuss the significance of SARS-CoV-1, SARS-CoV-2, as well as the Middle East respiratory syndrome coronavirus (MERS-CoV) in Saudi Arabia with particular reference to global transmission and/or emergence of new variants due to genetic mixing of different strains. Furthermore, we also discuss the role of Saudi Arabia with reference to novel emerging infectious diseases and re-emerging infections, such as Ebola, zika, and monkeypox, as well as in the context on coinfections. Future strategies to limit the spread of viral infections and the pivotal role of Saudi Arabia, are deliberated upon.
尽管抗菌治疗和支持性护理取得了进展，但全球范围内因传染病导致的死亡率仍在持续上升。这在由严重急性呼吸综合征冠状病毒2（SARS-CoV-2）引发的2019冠状病毒病（COVID-19）大流行中表现得很明显。沙特阿拉伯是阿拉伯地区的一个重要国家，在全球大流行期间产生了重大影响，与此同时，每年有数百万穆斯林前往沙特阿拉伯朝圣。在此，我们讨论沙特阿拉伯境内严重急性呼吸综合征冠状病毒1（SARS-CoV-1）、严重急性呼吸综合征冠状病毒2（SARS-CoV-2）以及中东呼吸综合征冠状病毒（MERS-CoV）的重要性，特别提及不同毒株基因混合导致的全球传播和/或新变种的出现。此外，我们还讨论沙特阿拉伯在新型新兴传染病和重新出现的感染（如埃博拉、寨卡和猴痘）方面的作用，以及在合并感染背景下的作用。我们还审议了限制病毒感染传播的未来策略以及沙特阿拉伯的关键作用。
