Alharbi Ahmad M
Department of Clinical Laboratories Sciences, College of Applied Medical Sciences, Taif University, Taif, 21944, Saudi Arabia.
Virus Res. 2025 Jan;351:199510. doi: 10.1016/j.virusres.2024.199510. Epub 2024 Dec 24.
Exacerbated by the rise of global warming due to climate change, as well as ease of international travel and mass migration, the dengue virus infection remains of particular economic and global concern. Of note, the emergence of the first case of dengue viral infection occurred in Saudi Arabia in the 1990s, and since then there has been a steady rise in the number of cases. Moreover, the arrival of imported dengue virus variants poses a significant challenge to dengue fever surveillance and control efforts within the region, especially as Saudi Arabia attracts millions of religious pilgrims throughout the year. Herein, we discuss the epidemiology of dengue viral infection in Saudi Arabia, dengue fever biology and clinical manifestation. Current management strategies, amongst other factors influencing dengue fever in Saudi Arabia are also deliberated upon. Future ongoing research and consistent monitoring of both established and emerging dengue viral strains within Saudi Arabia are needed, given the lack of current comprehensive studies.
气候变化导致的全球变暖加剧，以及国际旅行的便利和大规模移民，使得登革热病毒感染仍然是特别值得经济和全球关注的问题。值得注意的是，20世纪90年代沙特阿拉伯出现了首例登革热病毒感染病例，此后病例数量稳步上升。此外，输入性登革热病毒变种的出现对该地区的登革热监测和防控工作构成了重大挑战，尤其是因为沙特阿拉伯全年吸引数百万宗教朝圣者。在此，我们讨论沙特阿拉伯登革热病毒感染的流行病学、登革热生物学和临床表现。还审议了沙特阿拉伯登革热的当前管理策略以及其他影响因素。鉴于目前缺乏全面研究，需要对沙特阿拉伯境内已有的和新出现的登革热病毒株进行持续的研究和监测。
