Amirthalingam Sivabalaganesh, Kumar Pradeep, Harshavardhan J K Giriraj
Department of Orthopaedics, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
Department of Pediatric Orthopaedics , Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
J Orthop Case Rep. 2023 Jul;13(7):116-120. doi: 10.13107/jocr.2023.v13.i07.3776.
Osteoarthritis is now understood to be an aberrant remodeling of the joint organ caused by wear-and-tear mechanism and by a variety of inflammatory mediators. Subchondral cysts have been one of the important radiological features of knee osteoarthritis that is not well understood. We report a case of large subchondral lytic lesion which was initially thought to be a giant cell tumor and later was identified as subchondral cyst.
A 50-year-old man presented to the outpatient department with complaints of intermittent pain and swelling over the left knee associated with difficulty in performing his daily activities Patient had undergone cerclage wiring for fracture left patella fracture 8 years back following which pain started. Radiographs showed extensive degenerative change at the knee with a large, multilocular lytic lesion in the proximal tibia. Magnetic resonance imaging showed similar features with an additional lesion in the distal femur. Core needle biopsy and histopathological examination of both lesions showed fibrocollageous tissue with bone fragments and lymphocytes. Patient was treated conservatively with analgesics and physiotherapy. He had good relief of pain and is on regular follow-up till date.
Osteoarthritis knee is the most prevalent and leading cause of pain and disability worldwide. Subchondral cysts are strongly associated with osteoarthritis. Articular cartilage damage in osteoarthritis exposes the subarticular bone to injury, particularly in the weight-bearing joints. Large cysts are a well-recognized feature of other disorders such as simple bone cyst, aneurysmal bone cyst, giant cell tumor, and osteomyelitis. As these cases are rarely reported the treatment options are not standardized. Studies had shown similar cases treated both conservatively and surgically. The occurrence of the pathological fracture in these cases is high so prophylactic surgical fixation of massive geodes is advised. We decided to treat our case conservatively with analgesics and physiotherapy. The patient has good relief of pain at present and is on regular follow-up. He has been counseled that he may need a total knee replacement in the future if pain increases in severity.
In the presence of osteolytic lesion showing very large cyst with cortical expansion and septations in radiographs with adjacent joint arthritis, the diagnosis of subchondral cyst/Geode should be strongly considered.
目前认为骨关节炎是由磨损机制和多种炎症介质引起的关节器官异常重塑。软骨下囊肿一直是膝关节骨关节炎重要的影像学特征之一,但人们对此了解并不充分。我们报告一例大型软骨下溶骨性病变,最初被认为是巨细胞瘤,后来被确诊为软骨下囊肿。
一名50岁男性因左膝关节间歇性疼痛和肿胀伴日常活动困难就诊于门诊。患者8年前因左髌骨骨折接受了环扎钢丝固定术,术后开始出现疼痛。X线片显示膝关节广泛退行性改变,胫骨近端有一个大型多房溶骨性病变。磁共振成像显示类似特征,股骨远端还有一个病变。对两个病变进行的粗针活检和组织病理学检查显示为含有骨碎片和淋巴细胞的纤维胶原组织。患者接受了镇痛药和物理治疗的保守治疗。他的疼痛得到了明显缓解,至今仍在定期随访。
膝关节骨关节炎是全球最常见且导致疼痛和残疾的主要原因。软骨下囊肿与骨关节炎密切相关。骨关节炎中的关节软骨损伤使关节下骨易受损伤,尤其是在负重关节。大型囊肿是其他疾病如单纯性骨囊肿、动脉瘤样骨囊肿、巨细胞瘤和骨髓炎的一个公认特征。由于这些病例很少被报道,治疗方案并不规范。研究表明,类似病例采用了保守治疗和手术治疗。这些病例中病理性骨折的发生率很高,因此建议对大型骨囊肿进行预防性手术固定。我们决定对我们的病例采用镇痛药和物理治疗的保守治疗方法。患者目前疼痛明显缓解,正在定期随访。我们已告知他,如果疼痛严重程度增加,将来可能需要进行全膝关节置换。
在存在溶骨性病变,X线片显示有非常大的囊肿伴皮质扩张和分隔且伴有相邻关节关节炎的情况下,应高度考虑软骨下囊肿/骨囊肿的诊断。