Kandarkar Madhavi M, Jadhav Shivshankar, Kandarkar Sanket M, Vaidya Shubham
Department of Musculoskeletal Physiotherapy, Datta Meghe Institute of Medical Sciences, Wardha, IND.
Department of Orthopedic Surgery, Datta Meghe Institute of Medical Sciences, Wardha, IND.
Cureus. 2023 Aug 7;15(8):e43102. doi: 10.7759/cureus.43102. eCollection 2023 Aug.
Giant cell tumor of the bone (GCTB) is a benign bone tumor that can occasionally progress to malignancy, usually in chronic cases. It is a common benign and aggressive bone tumor that affects patients aged between 20 and 45 years. The most common location is the knee joint. It manifests as a painless or occasionally painful swelling over the affected area. A case of giant cell tumor (GCT) of the proximal tibia in a 72-year-old male is reported here, which was difficult to diagnose as it is rarely found in the geriatric age group. The patient came with a chief complaint of pain and swelling over his left knee for two months with a history of trauma to the knee a couple of times. On clinical examination, the patient had grade 3 tenderness and swelling on the anterolateral aspect of the knee extending toward the proximal tibia. The swelling was well-defined, smooth, firm, and uniform in consistency with dimensions of 15 cm × 12 cm. The swelling was moveable sideways, and the movement of the knee suggested that it was not attached to the underlying bone. As per the age and history of the rapid-growing lesion, we suspected malignancy, but clinical findings were pointing toward benign tumor. X-ray of the affected knee was done, which revealed a soft tissue mass with the involvement of the bone. Magnetic resonance imaging (MRI) of the knee revealed a soft tissue mass with the cortical breach. An open biopsy was done for the confirmation of the diagnosis, which was later reported and confirmed as a giant cell tumor of the proximal tibia. As bone tumor is associated with a cortical breach and pathological fracture, it was classified under Campanacci grade 3, for which an en bloc resection and open reduction and internal fixation with plate osteosynthesis with bone cementing and bone grafting were done followed by knee bending physiotherapy and gradual weight-bearing. Finally, the knee function was improved with pain relief.
骨巨细胞瘤(GCTB)是一种良性骨肿瘤,偶尔可进展为恶性,通常在病程较长的情况下。它是一种常见的良性侵袭性骨肿瘤,好发于20至45岁的患者。最常见的部位是膝关节。表现为受累部位无痛或偶尔疼痛性肿胀。本文报告一例72岁男性近端胫骨骨巨细胞瘤(GCT),因其在老年人群中罕见,故诊断困难。患者因左膝疼痛和肿胀为主诉前来就诊,病程两个月,有膝关节数次外伤史。临床检查时,患者膝关节前外侧至近端胫骨有3级压痛和肿胀。肿胀边界清晰,表面光滑,质地坚实且均匀一致,大小为15 cm×12 cm。肿胀可向侧面移动,膝关节活动提示其未与下方骨骼相连。根据病变快速生长的年龄和病史,我们怀疑为恶性,但临床检查结果指向良性肿瘤。对患侧膝关节进行了X线检查,显示有软组织肿块累及骨质。膝关节磁共振成像(MRI)显示有软组织肿块伴皮质破坏。为明确诊断进行了切开活检,后来报告并确诊为近端胫骨骨巨细胞瘤。由于骨肿瘤伴有皮质破坏和病理性骨折,故将其归类为Campanacci 3级,对此进行了整块切除、切开复位及钢板内固定,并使用骨水泥和植骨,随后进行膝关节弯曲理疗和逐渐负重。最后,膝关节功能得到改善,疼痛缓解。