Huang Chen-Yang, Sun Hai-Xiang, Mei Jie
Reproductive Medicine Center, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, China.
Center for Molecular Reproductive Medicine, Nanjing University, Nanjing 210008, China.
Reprod Dev Med. 2022 Sep;6(3):138-143. doi: 10.1097/RD9.0000000000000015. Epub 2022 Sep 30.
The impact of coronavirus disease 2019 (COVID-19) on endometriosis (EM) is currently unclear. Here, we aimed to describe the potential influence of COVID-19 on the pathogenesis, clinical symptoms, and treatment of EM. The cytokine storm caused by COVID-19 may induce the occurrence and progression of EM, and immunosuppression of COVID-19 may help the ectopic endometrium escape from immune clearance. Consequently, the forced social isolation and the cancelation of non-emergency medical treatment during the COVID-19 pandemic aggravate anxiety and psychological pressure, which can aggravate the symptoms related to EM and delay routine medical services.
2019冠状病毒病（COVID-19）对子宫内膜异位症（EM）的影响目前尚不清楚。在此，我们旨在描述COVID-19对EM的发病机制、临床症状及治疗的潜在影响。COVID-19引发的细胞因子风暴可能诱导EM的发生和进展，而COVID-19的免疫抑制作用可能有助于异位子宫内膜逃避免疫清除。因此，COVID-19大流行期间的强制社会隔离以及非紧急医疗服务的取消加剧了焦虑和心理压力，这会加重与EM相关的症状并延误常规医疗服务。
