Bampidis Vasileios, Azimonti Giovanna, Bastos Maria de Lourdes, Christensen Henrik, Durjava Mojca, Dusemund Birgit, Kouba Maryline, López-Alonso Marta, López Puente Secundino, Marcon Francesca, Mayo Baltasar, Pechová Alena, Petkova Mariana, Ramos Fernando, Sanz Yolanda, Villa Roberto Edoardo, Woutersen Ruud, Dierick Noël, Anguita Montserrat, Innocenti Matteo Lorenzo, Ortuño Jordi, Tarres-Call Jordi, Firmino Joana P
EFSA J. 2023 Jul 27;21(7):e08176. doi: 10.2903/j.efsa.2023.8176. eCollection 2023 Jul.
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety of acetic acid, calcium acetate and sodium diacetate as technological feed additives (preservatives) for salmonids/fish. The additives are already authorised for use for all animal species other than fish. In previous opinions, the FEEDAP Panel concluded that a maximum concentration of 2,500 mg acetic acid/kg complete feed (or 1,000 mg/L water for drinking) was safe for poultry, pigs and pet animals. Ruminants were considered to exhibit a higher tolerance. Due to lack of data for salmonids, the Panel could not conclude on the safety of acetic acid and its salts for fish. The applicant has provided supplementary information consisting in a tolerance study in Atlantic salmon () and a literature search to support the safety of acetic acid in fish. Considering all the available information, the FEEDAP Panel concluded that acetic acid (and its salts by analogy) is considered safe for fish up to the maximum recommended supplementation level of 2,500 mg acetic acid/kg complete feed.
应欧盟委员会的要求，欧洲食品安全局（EFSA）被要求就乙酸、醋酸钙和双乙酸钠作为鲑鱼/鱼类的技术饲料添加剂（防腐剂）的安全性提供科学意见。这些添加剂已被批准用于除鱼类以外的所有动物物种。在之前的意见中，饲料添加剂和产品（FEEDAP）小组得出结论，对于家禽、猪和宠物动物，每千克全价饲料中乙酸的最大浓度为2500毫克（或饮用水中为1000毫克/升）是安全的。反刍动物被认为具有更高的耐受性。由于缺乏鲑鱼的数据，该小组无法就乙酸及其盐类对鱼类的安全性得出结论。申请人提供了补充信息，包括一项大西洋鲑鱼（）的耐受性研究和一项文献检索，以支持乙酸在鱼类中的安全性。考虑到所有可用信息，FEEDAP小组得出结论，在每千克全价饲料中乙酸的最大推荐添加水平为2500毫克时，乙酸（及其类推的盐类）对鱼类被认为是安全的。
