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系统评价和荟萃分析：美国、加拿大和乌克兰（2010-2021 年）的 HIV 护理干预措施的关联性

Systematic Review and Meta-analysis of Linkage to HIV Care Interventions in the United States, Canada, and Ukraine (2010-2021).

机构信息

Division of General Internal Medicine, Department of Medicine, Massachusetts General Hospital, 100 Cambridge Street, Suite 1600, Boston, MA, 02114, USA.

Harvard Medical School, Boston, MA, USA.

出版信息

AIDS Behav. 2023 Dec;27(12):4070-4083. doi: 10.1007/s10461-023-04121-0. Epub 2023 Jul 31.

DOI:10.1007/s10461-023-04121-0
PMID:37523048
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10598185/
Abstract

We conducted a systematic review and meta-analysis of interventions targeting linkage to HIV care in the US, Canada, and Europe. We searched six databases (PubMed, Embase, Cochrane Library, Web of Science and CINAHL). Inclusion criteria were English language studies in adults in the US, Canada, or Europe, published January 1, 2010 to January 1, 2021. We synthesized interventions by type and linkage to care outcome. The outcome was cumulative incidence of 3-month linkage. We estimated cumulative incidence ratios of linkage with 95% confidence intervals (CIs). We screened 945 studies; 13 met selection criteria (n = 1 from Canada, n = 1 from Ukraine, n = 11 from the US) and were included after full text review (total 37,549 individuals). The cumulative incidence of 3-month linkage in the intervention group was 0.82 (95% CI 0.68-0.94) and control group 0.71 (95% CI 0.50-0.90); cIR of linkage for intervention versus control was 1.30 (95% CI 1.13, 1.49). Interventions to improve linkage to care after HIV diagnosis warrant further attention.

摘要

我们对美国、加拿大和欧洲针对 HIV 护理衔接的干预措施进行了系统评价和荟萃分析。我们检索了六个数据库（PubMed、Embase、Cochrane 图书馆、Web of Science 和 CINAHL）。纳入标准为在美国、加拿大或欧洲以成年人作为研究对象、发表于 2010 年 1 月 1 日至 2021 年 1 月 1 日的英文研究。我们按干预类型和与护理衔接结果进行了综合分析。结果是 3 个月衔接的累积发生率。我们用 95%置信区间（CI）估计了衔接的累积发生率比。我们筛选了 945 项研究；13 项符合入选标准（加拿大 1 项、乌克兰 1 项、美国 11 项），并在全文审查后纳入（共 37549 人）。干预组的 3 个月衔接累积发生率为 0.82（95%CI 0.68-0.94），对照组为 0.71（95%CI 0.50-0.90）；干预组与对照组的衔接校正累积发生率比为 1.30（95%CI 1.13, 1.49）。改善 HIV 诊断后护理衔接的干预措施值得进一步关注。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d6d/10598185/3d571f316493/10461_2023_4121_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d6d/10598185/320118bb33ff/10461_2023_4121_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d6d/10598185/1430530c62b3/10461_2023_4121_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d6d/10598185/5f754fb30021/10461_2023_4121_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d6d/10598185/3d571f316493/10461_2023_4121_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d6d/10598185/320118bb33ff/10461_2023_4121_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d6d/10598185/1430530c62b3/10461_2023_4121_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d6d/10598185/5f754fb30021/10461_2023_4121_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d6d/10598185/3d571f316493/10461_2023_4121_Fig4_HTML.jpg

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引用本文的文献

[1]
Impact of stigma on the HIV care cascade among older persons living with HIV in sub-Saharan Africa: protocol for a systematic review.

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[2]
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本文引用的文献

[1]
The PRISMA 2020 statement: an updated guideline for reporting systematic reviews.

BMJ. 2021-3-29

[2]
Community-based antiretroviral therapy versus standard clinic-based services for HIV in South Africa and Uganda (DO ART): a randomised trial.

Lancet Glob Health. 2020-10

[3]
Letter to the Readers.

Alcohol Clin Exp Res. 2020-6

[4]
Risk-of-bias VISualization (robvis): An R package and Shiny web app for visualizing risk-of-bias assessments.

Res Synth Methods. 2021-1

[5]
Modified Antiretroviral Treatment Access Study (MARTAS): A Randomized Controlled Trial of the Efficacy of a Linkage-to-Care Intervention Among HIV-Positive Patients in Ukraine.

AIDS Behav. 2020-11

[6]
HIV Testing and Linkage to Care Among Transgender Women Who Have Sex with Men: 23 U.S. Cities.

AIDS Behav. 2020-8

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J Assoc Nurses AIDS Care. 2020

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Int J Evid Based Healthc. 2020-3

[9]
Improving Timely Linkage to Care among Newly Diagnosed HIV-Infected Youth: Results of SMILE.

J Urban Health. 2019-12

[10]
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AIDS Behav. 2019-10

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