Department of Psychology, University of Oradea, Oradea, Romania.
The Hull York Medical School, University of York, York, United Kingdom.
PLoS One. 2023 Jul 31;18(7):e0288910. doi: 10.1371/journal.pone.0288910. eCollection 2023.
Improving the existent effective treatments of depression is a promising way to optimise the effects of psychological treatments. Here we examine the effects of adding a rehabilitation type of imagery based on exergames and dynamic simulations to a short behavioural activation treatment of depression. We investigate the acceptability and the efficacy of an exergame-augmented dynamic imagery intervention added to behavioural activation treatment and associated mechanisms of change.
In a two-arm pilot randomised controlled trial, the acceptability and preliminary efficacy of an exergame-augmented dynamic imagery intervention added to behavioural activation treatment for depressed individuals will be assessed. Participants (age 18-65) meeting criteria for depression are recruited by media and local announcements. 110 participants will be randomly allocated to behavioural activation plus imagery group or to standard behavioural activation group. The primary outcome is depressive symptom severity (Beck Depression Inventory II) and secondary outcomes are anhedonia, apathy and behavioural activation and avoidance. The outcomes are assessed at baseline, mid treatment, posttreatment and 3-month follow-up. Moderation and mediation analyses will be explored. An intention-to-treat approach with additional per-protocol analysis will be used for data analysis.
改善现有的有效抑郁症治疗方法是优化心理治疗效果的一种有前途的方法。在这里，我们研究了将基于运动游戏和动态模拟的康复型意象添加到短程行为激活治疗抑郁症中对其效果的影响。我们调查了将运动游戏增强的动态意象干预添加到行为激活治疗中以及相关的变化机制的可接受性和疗效。
在一项双臂先导随机对照试验中，将评估将运动游戏增强的动态意象干预添加到行为激活治疗中对抑郁个体的可接受性和初步疗效。通过媒体和当地公告招募符合抑郁症标准的参与者（年龄 18-65 岁）。110 名参与者将被随机分配到行为激活加意象组或标准行为激活组。主要结局指标是抑郁症状严重程度（贝克抑郁量表第二版），次要结局指标是快感缺失、冷漠和行为激活和回避。在基线、治疗中期、治疗后和 3 个月随访时评估结局。将探索调节和中介分析。将采用意向治疗方法和额外的方案分析进行数据分析。
