American College of Physicians, Philadelphia, Pennsylvania (A.Q., C.S.H.).
David Geffen School of Medicine at UCLA, Los Angeles, California (C.J.C.).
Ann Intern Med. 2023 Aug;176(8):1092-1100. doi: 10.7326/M23-0779. Epub 2023 Aug 1.
The purpose of this updated guidance statement is to guide clinicians on screening for colorectal cancer (CRC) in asymptomatic average-risk adults. The intended audience is all clinicians. The population is asymptomatic adults at average risk for CRC.
This updated guidance statement was developed using recently published and critically appraised clinical guidelines from national guideline developers since the publication of the American College of Physicians' 2019 guidance statement, "Screening for Colorectal Cancer in Asymptomatic Average-Risk Adults." The authors searched for national guidelines from the United States and other countries published in English using PubMed and the Guidelines International Network library from 1 January 2018 to 24 April 2023. The authors also searched for updates of guidelines included in the first version of our guidance statement. The Appraisal of Guidelines for Research and Evaluation II (AGREE II) instrument was used to assess the quality of eligible guidelines. Two guidelines were selected for adoption and adaptation by raters on the basis of the highest average overall AGREE II quality scores. The evidence reviews and modeling studies for these 2 guidelines were also used to synthesize the evidence of diagnostic test accuracy, effectiveness, and harms of CRC screening interventions and to develop our guidance statements.
GUIDANCE STATEMENT 1: .
GUIDANCE STATEMENT 2:
GUIDANCE STATEMENT 3:
GUIDANCE STATEMENT 4A:
GUIDANCE STATEMENT 4B:
GUIDANCE STATEMENT 4C:
本更新指南旨在指导临床医生对无症状一般风险成年人进行结直肠癌（CRC）筛查。目标受众是所有临床医生。人群为无 CRC 症状的一般风险成年人。
本更新指南是在 2019 年美国医师学院“无症状一般风险成年人结直肠癌筛查”指南发布后，使用最近发表的、经过严格评估的来自国家指南制定者的临床指南制定的。作者使用 PubMed 和指南国际网络图书馆，从 2018 年 1 月 1 日至 2023 年 4 月 24 日，搜索了以英文发表的来自美国和其他国家的国家指南。作者还搜索了我们第一版指南中包含的指南更新。采用了 AGREE II 工具评估合格指南的质量。根据 AGREE II 平均总分最高，选择了两条指南供评估者采用和改编。这两条指南的证据综述和建模研究也用于综合 CRC 筛查干预的诊断测试准确性、有效性和危害的证据，并制定我们的指南。
指南声明 1：.
指南声明 2：
指南声明 3：
指南声明 4A：
指南声明 4B：
指南声明 4C：
