Wu Di, Song Qi-Ying, Dai Bai-Shu, Li Jie, Wang Xin-Xin, Liu Jia-Yu, Xie Tian-Yu
Department of General Surgery, First Medical Centre of Chinese PLA General Hospital, Beijing 100853, China.
Department of Neurosurgery, First Medical Centre of Chinese PLA General Hospital, Beijing 100853, China.
World J Gastroenterol. 2025 Mar 7;31(9):98760. doi: 10.3748/wjg.v31.i9.98760.
Colorectal cancer (CRC) is a prevalent malignancy worldwide, posing a significant public health concern. Mounting evidence has confirmed that timely early screening facilitates the detection of incipient CRC, thereby enhancing patient prognosis. Obviously, non-participation of asymptomatic individuals in screening programs hampers early diagnosis and may adversely affect long-term outcomes for CRC patients. In this letter, we provide a comprehensive overview of the current status of early screening practices, while also thoroughly examine the dilemmas and potential solutions associated with early screening for CRC. In response to these issues, we proffer a set of recommendations directed at governmental authorities and the general public, which focus on augmenting financial investment, establishing standardized screening protocols, advancing technological capabilities, and bolstering public awareness campaigns. The importance of collaborative efforts from various stakeholders cannot be overstated in the quest to enhance early detection rates and alleviate the societal burden of CRC.
结直肠癌（CRC）是一种在全球范围内普遍存在的恶性肿瘤，引起了重大的公共卫生关注。越来越多的证据证实，及时进行早期筛查有助于发现早期结直肠癌，从而改善患者预后。显然，无症状个体不参与筛查计划会妨碍早期诊断，并可能对结直肠癌患者的长期预后产生不利影响。在这封信中，我们全面概述了早期筛查实践的现状，同时深入探讨了与结直肠癌早期筛查相关的困境及潜在解决方案。针对这些问题，我们向政府当局和公众提出了一系列建议，重点是增加财政投入、建立标准化筛查方案、提升技术能力以及加强公众宣传活动。在提高早期检测率和减轻结直肠癌社会负担的努力中，各利益相关方合作的重要性怎么强调都不为过。
