Department of Geriatric Dentistry, Hospital of Stomatology, Jilin University, China.
National and Local Joint Engineering Laboratory for Synthetic Technology of High-Performance Polymer, College of Chemistry, Jilin University, China.
J Mech Behav Biomed Mater. 2023 Sep;145:106047. doi: 10.1016/j.jmbbm.2023.106047. Epub 2023 Jul 27.
To investigate the mechanical properties, biosafety, and shearing bonding strength of glass fibers-reinforced polyether-ether-ketone (PEEK-GF) for post-core materials.
PEEK-GF composites with different glass fiber contents were prepared by extrusion injection and named PEEK-GF30, PEEK-GF40, and PEEK-GF50. Mechanical properties including flexural modulus, flexural strength, Vickers hardness, and compression strength were tested. The cross-sectional morphology was examined using scanning electron microscopy (SEM). Cytotoxicity was studied in vitro with Cell-counting kit-8 (CCK-8). Cell morphology was observed under a microscope. Cell growth on the composites' surfaces was analyzed with DAPI staining. The shearing bonding strength (SBS) of PEEK-GF50 was assessed after applying different pretreatments. Failure modes were evaluated by microscopy. SEM and contact-angle measurements were performed on the surfaces. Statistical analysis was conducted using one-way ANOVA (P < 0.05).
The mechanical properties of PEEK-GF composites improved with increased GF content. The PEEK-GF50 group exhibited flexural modulus (17.4 ± 0.5 GPa) close to that of dentin (18.6 GPa) and showed the highest flexural strength (350.0 ± 2.9 MPa), Vickers hardness (47.6 ± 4.5 HV), and compressive strength (264.0 ± 18.0 MPa). The SEM analysis demonstrated that the PEEK matrix combined well with glass fibers. The CCK-8 results confirmed the biosafety of all groups. DAPI staining indicated that cells were growing well on the composites' surface. The sample that was pretreated with sandblasting and plasma showed the highest SBS (16.0 ± 1.7 MPa).
The PEEK-GF composites demonstrated excellent mechanical properties, biosafety, and SBS, and have great potential to serve as post-core materials.
研究玻璃纤维增强聚醚醚酮（PEEK-GF）用于桩核材料的力学性能、生物安全性和剪切粘结强度。
通过挤出注塑制备不同玻璃纤维含量的 PEEK-GF 复合材料，分别命名为 PEEK-GF30、PEEK-GF40 和 PEEK-GF50。测试了弯曲模量、弯曲强度、维氏硬度和抗压强度等力学性能。采用扫描电子显微镜（SEM）观察了复合材料的横截面形貌。采用细胞计数试剂盒（CCK-8）进行体外细胞毒性研究。显微镜下观察细胞形态。通过 DAPI 染色分析细胞在复合材料表面的生长情况。对 PEEK-GF50 进行不同预处理后，评估其剪切粘结强度（SBS）。通过显微镜评估失效模式。对表面进行 SEM 和接触角测量。采用单因素方差分析（P<0.05）进行统计分析。
随着 GF 含量的增加，PEEK-GF 复合材料的力学性能得到提高。PEEK-GF50 组的弯曲模量（17.4±0.5 GPa）接近牙本质（18.6 GPa），并表现出最高的弯曲强度（350.0±2.9 MPa）、维氏硬度（47.6±4.5 HV）和抗压强度（264.0±18.0 MPa）。SEM 分析表明 PEEK 基体与玻璃纤维结合良好。CCK-8 结果证实了所有组别的生物安全性。DAPI 染色表明细胞在复合材料表面生长良好。经过喷砂和等离子预处理的样品显示出最高的 SBS（16.0±1.7 MPa）。
PEEK-GF 复合材料表现出优异的力学性能、生物安全性和 SBS，有望成为桩核材料。
