School of Material Science and Engineering, Taiyuan University of Technology, Taiyuan 030024, China.
Department of Prosthodontics, The First Hospital of Shanxi Medical University, Taiyuan 030001, China.
J Mech Behav Biomed Mater. 2019 Jan;89:227-233. doi: 10.1016/j.jmbbm.2018.09.040. Epub 2018 Sep 26.
Weak mechanical properties affect the application of PEEK as an implant. Carbon fiber (CFR) reinforcement provides an excellent solution to improve the mechanical strength of PEEK and to provide perfect matching of elastic modulus between CFR-PEEK composites and human bone. To investigate the effect of carbon fiber content on the mechanical, thermal properties and cytotoxicity of CFR reinforced PEEK composites, a series of CFR-PEEK composites with different carbon fiber content (25 wt%, 30 wt%, 35 wt%, 40 wt%) was prepared in this work. Thermal decomposition behavior and melting temperature were studied by thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC), respectively. Subsequently, mechanical properties including bending strength, compressive strength, impact strength and hardness were tested respectively. Afterwards, the fracture morphology of the bending test samples was observed by scanning electron microscopy (SEM). In addition, murine fibroblast L929 cells were adopted for cytotoxicity test by CCK-8 assay in vitro, and the morphology of cells was observed by inverted fluorescence microscope simultaneously, cell compatibility of CFR-PEEK composites was tested.
力学性能较弱限制了聚醚醚酮（PEEK）作为植入物的应用。碳纤维（CFR）增强为提高 PEEK 的力学强度，提供完美匹配 CFR-PEEK 复合材料与人骨的弹性模量提供了一个很好的解决方案。为了研究碳纤维含量对 CFR 增强 PEEK 复合材料的力学、热性能和细胞毒性的影响，本工作采用不同碳纤维含量（25wt%、30wt%、35wt%、40wt%）制备了一系列 CFR-PEEK 复合材料。通过热重分析（TGA）和差示扫描量热法（DSC）分别研究了热分解行为和熔融温度。随后，分别测试了弯曲强度、压缩强度、冲击强度和硬度等力学性能。之后，通过扫描电子显微镜（SEM）观察弯曲试验样品的断裂形貌。此外，采用 CCK-8 法体外测试了小鼠成纤维细胞 L929 的细胞毒性，同时通过倒置荧光显微镜观察细胞形态，测试了 CFR-PEEK 复合材料的细胞相容性。
