Smith D C, O'Connell P
Anaesthesia. 1986 Jul;41(7):745-8. doi: 10.1111/j.1365-2044.1986.tb12845.x.
The incidence of cardiac dysrhythmias during inpatient dental anaesthesia under halothane was studied following either hyoscine or droperidol as a supplement to papaveretum for premedication. Forty-three percent of patients given hyoscine exhibited cardiac dysrhythmias compared to 23 percent of the group given droperidol (p = 0.03). The incidence of dysrhythmias bore no relationship to the age, sex or weight of the patient, nor to the end tidal carbon dioxide tension.
研究了在氟烷麻醉下住院牙科手术中,使用东莨菪碱或氟哌利多作为辅助用药,与吗啡合用于术前用药时发生心律失常的情况。接受东莨菪碱的患者中有43%出现心律失常,而接受氟哌利多的患者组中这一比例为23%(p = 0.03)。心律失常的发生率与患者的年龄、性别或体重无关,也与呼气末二氧化碳分压无关。