Bradshaw E G
Anaesthesia. 1976 Jan-Feb;31(1):13-7. doi: 10.1111/j.1365-2044.1976.tb11739.x.
Seventy-eight fit adult patients undergoing minor oral surgery received one of three intravenous premedications or were unpremedicated. Cardiac rhythm was monitored during surgery. A significantly higher incidence of dysrhythmias was associated with intravenous atropine 0-3 mg/given prior to surgery. Droperidol 0-1 mg/kg did not act prophylactically as an anti-dysthythmic agent in comparison with the control group. A further trial of eighteen cases suggested that atropine 0-6 mg intramuscularly followed by controlled ventilation may be effective in preventing dysrhythmias.
78名身体健康的成年患者接受小型口腔手术，他们被给予三种静脉术前用药之一，或者未接受术前用药。手术期间监测心律。术前静脉注射0 - 3毫克/千克阿托品与明显更高的心律失常发生率相关。与对照组相比，0 - 1毫克/千克氟哌利多并无预防心律失常的作用。另一项18例患者的试验表明，肌肉注射0 - 6毫克阿托品后进行控制通气可能有效预防心律失常。
