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舞蹈/运动疗法对改善长期精神分裂症患者平衡能力和骨密度的影响:一项随机对照试验

Dance/movement therapy for improving balance ability and bone mineral density in long-term patients with schizophrenia: a randomized controlled trial.

作者信息

Guan Hengyong, Zhou Zhaoxia, Li Xipo, Pan Yanfen, Zou Zhenmin, Meng Xiangfei, Guan Kunya, Zhang Lie, Li Zhanmin, Li Xueling, Wei Baochun, Zhang Xuan, Li Weiqing, Han Dongmei, Li Zezhi, Xiu Meihong

机构信息

Hebei Province Veterans Hospital, Hebei, China.

Department of Nutritional and Metabolic Psychiatry, Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, China.

出版信息

Schizophrenia (Heidelb). 2023 Jul 31;9(1):47. doi: 10.1038/s41537-023-00373-w.

Abstract

Fractures are common accidents for long-term hospitalized patients with schizophrenia (SZ) in psychiatric hospitals, and once they occur, patients usually endure the pain of fractures for a long time. Accumulating evidence has supported the implementation of dance/movement therapy (DMT) as a promising intervention for patients with SZ. However, no research has been conducted to investigate its role in balance ability in SZ. This study was designed to investigate the efficacy of a 12-week DMT intervention in bone mineral density and balance ability in patients with SZ using a randomized, controlled trial design. A total of 58 veterans with SZ were randomly assigned to the DMT intervention group (n = 29) and the treatment-as-usual (TAU) group (n = 29). Bone mineral density (BMD) and balance ability were measured in both groups at two measurement points (at baseline and at the end of Week 12). We found that patients in the DMT intervention group had significant improvements in BMD and balance ability compared with the TAU group by using repeated measures analysis of variance. Treatment with DMT demonstrated a significant improvement in BMD from baseline to week 12 (0.03, 95% CI: 0.01-0.05). For the Berg total score and static and dynamic balance, the mean changes in the DMT group were 7.3 (95% CI: 5.6-9.0), 4.0 (95% CI: 0.9-7.1), and 3.7 (95% CI: 2.6-4.8), respectively. Regression analysis showed that baseline BMD was a significant predictor of improvement in BMD from baseline to week 12 in the DMT group (β = 0.58, p < 0.001). Our results suggest for the first time that DMT intervention may be effective in beneficially regulating BMD and balance ability in SZ patients.

摘要

骨折是精神病医院中患有精神分裂症(SZ)的长期住院患者常见的意外情况,一旦发生,患者通常要长时间忍受骨折带来的疼痛。越来越多的证据支持将舞蹈/运动疗法(DMT)作为一种对SZ患者有前景的干预措施。然而,尚未有研究调查其在SZ患者平衡能力方面的作用。本研究旨在采用随机对照试验设计,调查为期12周的DMT干预对SZ患者骨密度和平衡能力的疗效。共有58名患有SZ的退伍军人被随机分配到DMT干预组(n = 29)和常规治疗(TAU)组(n = 29)。在两个测量点(基线时和第12周结束时)对两组患者的骨密度(BMD)和平衡能力进行了测量。通过重复测量方差分析,我们发现与TAU组相比,DMT干预组患者的BMD和平衡能力有显著改善。从基线到第12周,DMT治疗使BMD有显著改善(0.03,95%置信区间:0.01 - 0.05)。对于伯格总分以及静态和动态平衡,DMT组的平均变化分别为7.3(95%置信区间:5.6 - 9.0)、4.0(95%置信区间:0.9 - 7.1)和3.7(95%置信区间:2.6 - 4.8)。回归分析表明,基线BMD是DMT组从基线到第12周BMD改善的显著预测因素(β = 0.58,p < 0.001)。我们的结果首次表明,DMT干预可能对有益调节SZ患者的BMD和平衡能力有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0077/10390548/88056705e9fe/41537_2023_373_Fig1_HTML.jpg

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