Eye Center, School of Medicine, The Second Affiliated Hospital, Zhejiang University, 88 Jiefang Road, Hangzhou, 310009, Zhejiang, China.
Zhejiang Provincial Key Laboratory of Ophthalmology, Hangzhou, Zhejiang, China.
Sci Rep. 2023 Jul 31;13(1):12393. doi: 10.1038/s41598-023-39332-x.
We assessed the effectiveness of light-guided-tip intense pulsed light (IPL) with meibomian gland expression (MGX) in chalazion treatment. Ninety-five eyes with chalazion received a light-guided-tip IPL-MGX treatment (IPL-MGX group), and another 95 eyes with chalazion received incision with curettage treatment (Control group). Prior to IPL or incision, as well as 1 month after the final treatment, data were gathered pertaining to the lesion location and size, hyperemia, lesions regression or recurrence, and a comprehensive ophthalmic examination. The total size of the chalazia in the IPL-MGX group was significantly reduced after the final treatment, with an average resolution rate of 70.5%, which is comparable to excision surgery. A significant decrease in chalazion recurrence rate was apparent after treatment in the IPL-MGX group compared with control. Moreover, the IPL-MGX demonstrated significant advancements throughout noninvasive tear film breakup time (NIBUT) as well as meibum grade in comparison to baseline and those in the the Control group. The use of IPL-MGX was found to be an efficient therapy for reducing the size and recurring frequency of chalazia, as well as for improving the meibomian gland function. It may be considered as a first-line treatment for cases of primary or recurrent chalazia with inflammation.
我们评估了光引导尖端强脉冲光（IPL）联合睑板腺挤压（MGX）治疗睑板腺囊肿的疗效。95 例睑板腺囊肿患者接受了光引导尖端 IPL-MGX 治疗（IPL-MGX 组），95 例睑板腺囊肿患者接受了切开刮除术治疗（对照组）。在 IPL 或切开术之前以及最后一次治疗后 1 个月，收集了病变位置和大小、充血、病变消退或复发以及全面眼科检查的数据。IPL-MGX 组治疗后睑板腺囊肿的总体大小明显缩小，平均消退率为 70.5%，与切除术相当。与对照组相比，IPL-MGX 组治疗后睑板腺囊肿的复发率显著降低。此外，与基线相比以及与对照组相比，IPL-MGX 治疗后非侵入性泪膜破裂时间（NIBUT）和睑板腺等级均显著提高。使用 IPL-MGX 治疗可有效减少睑板腺囊肿的大小和复发频率，改善睑板腺功能。对于有炎症的原发性或复发性睑板腺囊肿，它可以被认为是一线治疗方法。
