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本文引用的文献

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Macular Retinoschisis from Optic Disc without a Visible Optic Pit or Advanced Glaucomatous Cupping (No Optic Pit Retinoschisis [NOPIR]).黄斑视网膜劈裂症（无可见视盘凹陷或高级青光眼性杯状凹陷）（无视盘凹陷性视网膜劈裂症[NOPIR]）。
Ophthalmol Retina. 2023 Sep;7(9):811-818. doi: 10.1016/j.oret.2023.05.020. Epub 2023 Jun 2.
2
Topographic Relationships among Deep Optic Nerve Head Parameters in Patients with Primary Open-Angle Glaucoma.原发性开角型青光眼患者深部视神经乳头参数之间的地形关系
J Clin Med. 2022 Feb 27;11(5):1320. doi: 10.3390/jcm11051320.
3
Risk factors for failure of resolving optic disc pit maculopathy after primary vitrectomy without laser photocoagulation.初次玻璃体切除术后不进行激光光凝治疗视盘小凹黄斑病变的失败风险因素。
Jpn J Ophthalmol. 2021 Nov;65(6):786-796. doi: 10.1007/s10384-021-00866-0. Epub 2021 Sep 9.
4
Papillomacular retinoschisis associated with glaucoma: Response to topical carbonic anhydrase inhibitor.与青光眼相关的黄斑部视网膜劈裂：对局部碳酸酐酶抑制剂的反应
Am J Ophthalmol Case Rep. 2020 May 19;19:100741. doi: 10.1016/j.ajoc.2020.100741. eCollection 2020 Sep.
5
Vitrectomy with peripapillary internal limiting membrane peeling for macular retinoschisis associated with normal-tension glaucoma.玻璃体切除术联合视乳头周围内界膜剥除术治疗与正常眼压性青光眼相关的黄斑视网膜劈裂症
Am J Ophthalmol Case Rep. 2020 Mar 17;18:100663. doi: 10.1016/j.ajoc.2020.100663. eCollection 2020 Jun.
6
Case Report: Glaucoma-associated Peripapillary Retinoschisis with Corresponding Lamina Cribrosa Defect.病例报告：青光眼相关性视乳头周围视网膜劈裂伴相应筛板缺损
Optom Vis Sci. 2020 Feb;97(2):104-109. doi: 10.1097/OPX.0000000000001474.
7
Optic Disc Pit Maculopathy: A Review.视盘小凹黄斑病变：综述。
Asia Pac J Ophthalmol (Phila). 2019 May-Jun;8(3):247-255. doi: 10.22608/APO.2018473.
8
Border Tissue Morphology Is Spatially Associated with Focal Lamina Cribrosa Defect and Deep-Layer Microvasculature Dropout in Open-Angle Glaucoma.眼前节组织形态与开角型青光眼局灶性筛板缺陷和深层微血管丢失呈空间相关。
Am J Ophthalmol. 2019 Jul;203:89-102. doi: 10.1016/j.ajo.2019.02.023. Epub 2019 Feb 28.
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Invest Ophthalmol Vis Sci. 2019 Jan 2;60(1):26-35. doi: 10.1167/iovs.18-25837.
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Deep Optic Nerve Head Morphology Is Associated With Pattern of Glaucomatous Visual Field Defect in Open-Angle Glaucoma.深视盘形态与开角型青光眼的青光眼视野缺损模式相关。
Invest Ophthalmol Vis Sci. 2018 Aug 1;59(10):3842-3851. doi: 10.1167/iovs.18-24588.

青光眼伴黄斑视网膜劈裂的光学相干断层扫描表现。

Optical coherence tomographic findings of glaucomatous eyes with papillomacular retinoschisis.

机构信息

Department of Ophthalmology, Kyorin University, School of Medicine, Tokyo, Japan.

出版信息

Eye (Lond). 2024 Feb;38(2):266-273. doi: 10.1038/s41433-023-02671-0. Epub 2023 Jul 31.

DOI:10.1038/s41433-023-02671-0
PMID:37524830
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10811323/
Abstract

OBJECTIVES

To investigate the relationship between the shape of the optic nerve head (ONH) margin detected by optical coherence tomography (OCT) and the clinical characteristics of glaucomatous eyes with papillomacular retinoschisis (PMRS).

METHODS

The medical record of patients with a PMRS in a glaucomatous eye were reviewed. The eyes were placed into two groups determined by the shape of the ONH margin in the OCT images; eyes with an externally oblique ONH margin (Group 1) and eyes with an internally oblique ONH margin (Group 2). We compared the clinical characteristics of the PMRS of these two groups.

RESULTS

We studied 31 eyes of 29 patients with PMRS and glaucoma with 24 eyes in Group 1 and 7 eyes in Group 2. The optic nerve fibre layer schisis on the lamina cribrosa (LC), beta zone, and gamma zone, and found that the LC defects were detected significantly more frequently in Group 1 than in Group 2 eyes (P < 0.05). A retinal nerve fibre schisis was observed around the ONH significantly more frequently in Group 2 than in Group 1 eyes (P < 0.01).

CONCLUSION

The cases of glaucoma-associated PMRS could be classified into two groups according to the obliquity of the ONH. They had differences in the findings of OCT and FA. The possibility that the mechanism of PMRS development is different in both groups is suggested.

摘要

目的

探讨光学相干断层扫描（OCT）检测到的视神经头（ONH）边缘形状与伴有黄斑神经视网膜劈裂（PMRS）的青光眼眼的临床特征之间的关系。

方法

回顾了青光眼合并 PMRS 患者的病历。根据 OCT 图像中 ONH 边缘的形状将这些眼分为两组：ONH 边缘外斜组（第 1 组）和 ONH 边缘内斜组（第 2 组）。我们比较了这两组 PMRS 的临床特征。

结果

我们研究了 31 只患有 PMRS 和青光眼的眼，其中 24 只眼位于第 1 组，7 只眼位于第 2 组。在筛板层（LC）、β区和γ区的神经纤维层劈裂，发现 LC 缺损在第 1 组中比第 2 组更频繁地检测到（P < 0.05）。在第 2 组中，ONH 周围的视网膜神经纤维劈裂明显比第 1 组更频繁（P < 0.01）。

结论

根据 ONH 的倾斜度，青光眼相关性 PMRS 病例可分为两组。它们在 OCT 和 FA 的发现上存在差异。提示两组 PMRS 发展的机制可能不同。