与青光眼相关的黄斑部视网膜劈裂：对局部碳酸酐酶抑制剂的反应
Papillomacular retinoschisis associated with glaucoma: Response to topical carbonic anhydrase inhibitor.
作者信息
Haruta Masatoshi, Handa So, Yoshida Shigeo
机构信息
Department of Ophthalmology, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka, 830-0011, Japan.
出版信息
Am J Ophthalmol Case Rep. 2020 May 19;19:100741. doi: 10.1016/j.ajoc.2020.100741. eCollection 2020 Sep.
PURPOSE
We report the clinical courses of two patients with papillomacular retinoschisis in eyes with advanced glaucomatous optic neuropathy.
OBSERVATIONS
In case 1, a 67-year-old woman was diagnosed with papillomacular retinoschisis and normal tension glaucoma in the left eye. Her medication was switched from topical latanoprost to brinzolamide, resulting in gradual improvement in the papillomacular retinoschisis thereafter. In case 2, a 76-year-old man was diagnosed with papillomacular retinoschisis, foveal detachment, and normal tension glaucoma in the left eye. His medication was switched from topical tafluprost/timolol to brinzolamide, resulting in gradual improvement in the papillomacular retinoschisis and foveal detachment thereafter.
CONCLUSIONSAND IMPORTANCE
Papillomacular retinoschisis may occur in eyes with advanced glaucomatous optic neuropathy. Topical brinzolamide therapy may lead to improvement of papillomacular retinoschisis.
目的
我们报告了两名患有晚期青光眼性视神经病变的眼睛发生乳头黄斑视网膜劈裂的患者的临床病程。
观察结果
病例1中，一名67岁女性被诊断为左眼乳头黄斑视网膜劈裂和正常眼压性青光眼。她的用药从局部用拉坦前列素改为布林佐胺，此后乳头黄斑视网膜劈裂逐渐改善。病例2中，一名76岁男性被诊断为左眼乳头黄斑视网膜劈裂、黄斑脱离和正常眼压性青光眼。他的用药从局部用他氟前列素/噻吗洛尔改为布林佐胺，此后乳头黄斑视网膜劈裂和黄斑脱离逐渐改善。
结论与意义
乳头黄斑视网膜劈裂可能发生在晚期青光眼性视神经病变的眼睛中。局部用布林佐胺治疗可能会使乳头黄斑视网膜劈裂得到改善。
Zotero 插件