Department of Pediatric Orthopaedics, Children's Hospital of Fudan University, National Children's Medical Center, 201102, Shanghai, China.
Department of Pediatric Orthopaedics, Hainan Women and Children's Medical Center, Haikou, 570206, China.
J Orthop Traumatol. 2023 Jul 31;24(1):39. doi: 10.1186/s10195-023-00717-3.
Ollier's disease can cause severe length discrepancy of the lower extremities and deformity in children. Osteotomy and limb lengthening with external fixation can correct the limb deformity. This study evaluated (1) whether the duration of external fixation was reduced in patients with Ollier's disease, and (2) the incidence of complications such as pin tract infection, external fixation loosening, and joint stiffness.
Two groups were compared with respect to age, angular correction (AC), lengthening gap (LG), distraction index (DI), lengthening length (LL), lengthening length percentage (L%), lengthening index (LI), bone healing index (BHI), and external fixation index (EFI). Group 1 (Ollier's disease) comprised nine patients undergoing 11 lower limb lengthening procedures using external fixators; group 2 (control, normal lengthened bone) comprised 28 patients undergoing 29 lengthening procedures with external fixators.
In patients with Ollier's disease, full correction of the deformity and full restoration of length were achieved in all cases. In the femur, the mean AC (15.97° vs. 6.72°) and DI (1.11 mm/day vs. 0.78 mm/day) were significantly larger, while the LI (9.71 days/cm vs. 13.49 days/cm), BHI (27.00 days/cm vs. 42.09 days/cm), and EFI (37.86 days/cm vs. 56.97 days/cm) were all significantly shorter in group 1 than in group 2 (p < 0.05). In the tibia, the mean AC and L% were larger, while the LG, LI, BHI, and EFI were all shorter in group 1 than in group 2. There was no significant difference between the two groups in the incidence of complications.
In children with Ollier's disease, new bone formation accelerated and the healing speed of the lengthened segments was faster throughout the whole lengthening period with external fixation, and full correction of the deformity and full restoration of length could be achieved.
奥利尔病可导致儿童下肢严重长度差异和畸形。截骨和肢体延长伴外固定架可矫正肢体畸形。本研究评估了（1）奥利尔病患者的外固定时间是否缩短，（2）针道感染、外固定松动和关节僵硬等并发症的发生率。
比较两组患者的年龄、角度矫正（AC）、延长间隙（LG）、延长指数（DI）、延长长度（LL）、延长长度百分比（L%）、延长指数（LI）、骨愈合指数（BHI）和外固定指数（EFI）。第 1 组（奥利尔病）包括 9 例采用外固定架行 11 例下肢延长术的患者；第 2 组（对照组，正常延长骨）包括 28 例采用外固定架行 29 例延长术的患者。
在奥利尔病患者中，所有病例均完全矫正畸形并完全恢复长度。在股骨中，平均 AC（15.97°比 6.72°）和 DI（1.11mm/天比 0.78mm/天）显著增大，而 LI（9.71 天/cm 比 13.49 天/cm）、BHI（27.00 天/cm 比 42.09 天/cm）和 EFI（37.86 天/cm 比 56.97 天/cm）均显著缩短。在胫骨中，平均 AC 和 L%较大，而 LG、LI、BHI 和 EFI 均较短。两组并发症发生率无显著差异。
在奥利尔病儿童中，新骨形成加速，外固定整个延长期内延长段的愈合速度加快，可实现畸形的完全矫正和长度的完全恢复。
