生物膜及其在疾病中的作用。
Biofilms and their role on diseases.
机构信息
Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY, 14642, USA.
College of Veterinary Medicine, Long Island University, Brookville, NY, 11548, USA.
出版信息
BMC Microbiol. 2023 Jul 31;23(1):203. doi: 10.1186/s12866-023-02954-2.
Abstract
Biofilms are complex, three-dimensional structures that provide a long-established survival mechanism for microorganisms. Biofilms play a substantial role in pathogenesis as they can evade the immune response and be highly resistant to conventional antimicrobials, thus impacting the human health and healthcare system. To address this issue, BMC Microbiology invites submissions to the collection 'Biofilms and its impact on disease'.
摘要
生物膜是一种复杂的三维结构，为微生物提供了一种长期存在的生存机制。生物膜在发病机制中起着重要作用，因为它们可以逃避免疫反应，并且对常规抗菌药物具有高度耐药性，从而对人类健康和医疗保健系统产生影响。为了解决这个问题，BMC 微生物学邀请大家向“生物膜及其对疾病的影响”专题投稿。
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Microorganisms. 2020 Aug 11;8(8):1222. doi: 10.3390/microorganisms8081222.
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