乌克兰领土上战争事件期间患者慢性非传染性躯体疾病过程的结构和动态。
Structure and dynamics of the course of chronic non-infectious somatic diseases in patients during war events on the territory of Ukraine.
机构信息
Department of Therapeutic Disciplines, Institute of Medicine of Petro Mohyla Black Sea National University, Mykolaiv, Ukraine.
Department of Pediatric and Surgical Disciplines, Institute of Medicine of Petro Mohyla Black Sea National University, Mykolaiv, Ukraine.
出版信息
BMC Public Health. 2023 Jul 31;23(1):1464. doi: 10.1186/s12889-023-16394-0.
BACKGROUND
The work studied and compared the dynamics of changes in the course of hypertension, type 2 diabetes, and somatized disorders in Ukrainian population, in the 1st period before war (October 2021 - February 2022) and 2nd period during the war (March -July 2022). The choice of the study of the above-mentioned nosology is due, first of all, to the increase in cases of referrals to outpatient doctors regarding hypertensive crises, the increase in the frequency of patients' complaints about the lability of glycemic indicators during routine monitoring of glucose levels with ambulatory glucometers, the appearance of chronic pain syndrome of unspecified pathology with the beginning of war events.
METHODS
272 people were examined in Mykolaiv Region (Ukraine). The patients were divided into three clinical groups: 1st group - 90 people patients with arterial hypertension; 2nd group - 92 people with type 2 diabetes; the 3rd group - 90 people with somatiform disorders.
RESULTS
In the patients of the 1st group during the 2nd period, amount of people with hypertension of the 1st stage increased in 1.8 times (p = 0.0412), with 2nd stage hypertension increased in 2 times (p = 0.0491) and 3rd stage hypertension increased in 2.5 times (p = 0.0391); somatized disorders in 3rd group also increased in 4.1 times (p = 0.001 < 0.05); in 2nd group recorded an increase in HbA1c by 0.99 ± 0.57 mmol/l (p = 1.795e-07 < 0.05), in comparison with the indicators for the 1st observation period.
CONCLUSIONS
The war events in Ukraine not only changed the life of every Ukrainian, but also had a significant impact on the dynamics and structure of chronic somatic diseases, in particular due to an increase in patient referrals for hypertensive crises, exacerbations of type 2 diabetes, somatized disorders, and chronic pain syndrome of unknown etiology. Considering these results, it is important to increase the equipment of regional primary care centers with antihypertensive, hypoglycemic and sedative drugs.
背景
本研究旨在比较乌克兰人群在战争前第一阶段（2021 年 10 月至 2022 年 2 月）和战争期间第二阶段（2022 年 3 月至 7 月）中高血压、2 型糖尿病和躯体化障碍病程变化的动态。选择研究上述疾病分类主要是由于高血压危象患者就诊增加，在使用动态血糖仪常规监测血糖时，患者血糖指标波动的频率增加，战争事件开始时出现了不明病因的慢性疼痛综合征。
方法
在乌克兰的尼古拉耶夫地区共检查了 272 人。患者被分为三组：第一组 90 人，为高血压患者；第二组 92 人，为 2 型糖尿病患者；第三组 90 人，为躯体化障碍患者。
结果
在第二阶段，第一组患者中，I 期高血压患者增加了 1.8 倍（p=0.0412），II 期高血压患者增加了 2 倍（p=0.0491），III 期高血压患者增加了 2.5 倍（p=0.0391）；第三组躯体化障碍患者增加了 4.1 倍（p=0.001<0.05）；第二组患者 HbA1c 增加了 0.99±0.57mmol/l（p=1.795e-07<0.05），与第一观察期的指标相比。
结论
乌克兰的战争事件不仅改变了每个乌克兰人的生活，还对慢性躯体疾病的动态和结构产生了重大影响，特别是由于高血压危象、2 型糖尿病加重、躯体化障碍和不明病因的慢性疼痛综合征患者就诊增加。考虑到这些结果，增加地区初级保健中心的抗高血压、降血糖和镇静药物设备非常重要。
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