Department of Otolaryngology-Head and Neck Surgery, University of California San Francisco, San Francisco.
Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Palo Alto, California.
Otol Neurotol. 2023 Sep 1;44(8):813-816. doi: 10.1097/MAO.0000000000003976. Epub 2023 Jul 29.
To assess changes in cognitive function in vestibular migraine patients undergoing treatment.
Prospective cohort.
Single-institution tertiary-care center.
Thirty-four patients with vestibular migraine were included in the study. Average age at diagnosis was 47.9 years. A majority of patients (91.2%) were female.
Vestibular therapies included pharmacologic treatment (67.6%), mindfulness-based stress reduction (58.8%), vestibular physical therapy (20.6%), and lifestyle changes only (2.9%).
Pretreatment and posttreatment questionnaires were collected including the Cognitive Failures Questionnaire (CFQ), Vestibular Migraine Patient Assessment Tool and Handicap Inventory (VM-PATHI), and Dizziness Handicap Inventory.
Median time between pretreatment and posttreatment questionnaire was 4.4 months (range, 2.8-15.6. mo). CFQ scores decreased in subjects who responded to treatment, as defined by those with a positive change in VM-PATHI score (average decrease, 6.5; p = 0.03). CFQ scores did not improve in subjects who had no improvement in their vestibular condition, as defined by no change or an increase in VM-PATHI score (average increase, 2.0; p = 0.53). Univariate linear regression showed that VM-PATHI score change was highly predictive of CFQ change ( p < 0.01, r2 = 0.36). Multivariate regression demonstrated that the VM-PATHI ( p = 0.03) and not the Dizziness Handicap Inventory ( p = 0.10) predicted changes in CFQ score.
Self-reported cognitive dysfunction improves with successful treatment of vestibular migraine.
评估前庭性偏头痛患者接受治疗后认知功能的变化。
前瞻性队列研究。
单机构三级护理中心。
34 例前庭性偏头痛患者纳入本研究。诊断时的平均年龄为 47.9 岁。大多数患者（91.2%）为女性。
前庭治疗包括药物治疗（67.6%）、正念减压（58.8%）、前庭物理治疗（20.6%）和仅生活方式改变（2.9%）。
收集治疗前和治疗后问卷，包括认知失败问卷（CFQ）、前庭偏头痛患者评估工具和残疾量表（VM-PATHI）以及头晕残疾量表。
治疗前和治疗后问卷中位数时间间隔为 4.4 个月（范围，2.8-15.6 个月）。根据 VM-PATHI 评分变化定义的对治疗有反应的患者（平均变化，6.5；p=0.03），CFQ 评分降低。根据 VM-PATHI 评分无变化或增加（平均增加，2.0；p=0.53）定义的前庭状况无改善的患者，CFQ 评分未改善。单变量线性回归显示，VM-PATHI 评分变化与 CFQ 变化高度相关（p<0.01，r2=0.36）。多元回归表明，VM-PATHI（p=0.03）而不是头晕残疾量表（p=0.10）预测 CFQ 评分变化。
前庭性偏头痛成功治疗后，自我报告的认知功能障碍得到改善。
