Subramanyam Chaitra, Gunt Hemali B, Sivamani Raja K
Integrative Skin Science and Research, Sacramento, CA, USA.
Western University of Health Sciences, Lebanon, OR, USA.
Clin Cosmet Investig Dermatol. 2023 Jul 26;16:1955-1961. doi: 10.2147/CCID.S417214. eCollection 2023.
The vermillion lip has unique physical properties and environmental exposures make them prone to dryness and chapping. While lips contribute to facial beauty, perioral aging is highly individual and dependent on ethnicity. Specifically with regard to South Asian population, there is no other literature identified on the biophysical characteristics of the vermillion lip.
In this work, characteristics of the vermillion skin in South Asians were examined through various clinical and biophysical characteristics of the lips such as dryness and roughness, fine lip lines, lip texture, hydration, and barrier function. Healthy South Asian females, from age 20-45 were recruited for this study and transepidermal water loss (TEWL), hydration, visual lip tolerance, and visual dryness were measured and graded by the dermatologist-investigator.
Lip texture and fine lines significantly increased from the 20s to the 40s. Overall lip health significantly decreased with age. TEWL and dryness increased with age while hydration decreased with age, although not significantly so.
This first-of-its kind study on South Asian females establishes that with age there is a decrease in overall lip health and an increase in signs of aging of the lips (fine lines, texture) from the 20s to 40s.
朱红色嘴唇具有独特的物理特性，且环境暴露使其容易干燥和皲裂。嘴唇虽有助于面部美观，但口周衰老具有高度个体差异且取决于种族。具体而言，关于南亚人群，尚未发现有关朱红色嘴唇生物物理特征的其他文献。
在本研究中，通过嘴唇的各种临床和生物物理特征，如干燥度和粗糙度、细纹、唇质地、水合作用和屏障功能，来检查南亚人朱红色皮肤的特征。招募年龄在20至45岁之间的健康南亚女性参与本研究，由皮肤科研究人员测量并分级经表皮水分流失（TEWL）、水合作用、视觉唇部耐受性和视觉干燥度。
从20多岁到40多岁，唇质地和细纹显著增加。总体唇部健康状况随年龄增长显著下降。TEWL和干燥度随年龄增长而增加，而水合作用随年龄增长而下降，尽管下降不显著。
这项针对南亚女性的同类首次研究表明，从20多岁到40多岁，随着年龄增长，总体唇部健康状况下降，唇部衰老迹象（细纹、质地）增加。
