Difunctional Fluorescent Probes for Iron and Hydrogen Sulfide Detection Based on Diphenyl Derivative.

In order to better monitor the content of Fe and HS in the biological environment, two new fluorescent probes were designed and synthesized. With the addition of Fe, the strong fluorescence emission of two probes was significantly quenched due to the paramagnetic effect of Fe. With the further addition of S, the fluorescence intensity was quickly restored. Two probes showed high selectivity and strong sensitivity for the detection of Fe and S, and the fluorescence intensity "ON-OFF-ON" was accompanied with the interaction process. At the same time, two probes displayed good anti-interference ability which was not interfered by the existence of other ions. In addition, two probes illustrated fast response time to Fe, S and small cytotoxicity to cells. Therefore, two probes can provide a potential ideal tool for detecting Fe and HS in organisms and the environment.