艾氯胺酮滴鼻剂对低温等离子体消融扁桃体切除术后儿童疼痛的影响。
Effect of esketamine nasal drops on pain in children after tonsillectomy using low temperature plasma ablation.
作者信息
Qian Qiu, Liu Hua Xian, Li Yue Qing
机构信息
Department of Anesthesiology, Suzhou Wujiang District Children's Hospital, Suzhou, China.
Department of Anesthesiology, Children's Hospital of Soochow University, Suzhou, China.
出版信息
Front Pediatr. 2023 Jul 17;11:1110632. doi: 10.3389/fped.2023.1110632. eCollection 2023.
OBJECTIVE
To explore the effect of esketamine nasal drops on pain in children after tonsillectomy using low-temperature plasma ablation.
METHODS
76 children who underwent tonsillectomy between May 2020 and July 2021, were randomly divided into two groups of 38 cases each. Patients in the control group were treated with conventional medication, while those in the study group were treated with esketamine nasal drops, along with the routine drug treatment. Pain levels of children in the two groups were compared within 1-3 days post-surgery, and the pseudomembrane formation and shedding-off time and recovery time were statistically analyzed.
RESULTS
The pain level of children in the study group was lower than that of the control group 1-3 days post-surgery. The pseudomembrane formation and shedding-off time and recovery time in the study group were shorter than in the control group (< 0.05). There was no significant difference in the incidence of adverse reactions between the two groups, and there were no serious adverse reactions in the two groups (> 0.05).
CONCLUSION
It is safe to use esketamine nasal drops in children after tonsillectomy using low temperature plasma ablation, and this is found to reduce pain and shorten the recovery time.
目的
探讨艾司氯胺酮滴鼻剂对低温等离子体消融扁桃体切除术后儿童疼痛的影响。
方法
选取2020年5月至2021年7月间行扁桃体切除术的76例儿童，随机分为两组，每组38例。对照组采用常规药物治疗，研究组在常规药物治疗基础上加用艾司氯胺酮滴鼻剂。比较两组患儿术后1 - 3天的疼痛程度，并对假膜形成及脱落时间、恢复时间进行统计学分析。
结果
术后1 - 3天，研究组患儿的疼痛程度低于对照组。研究组假膜形成及脱落时间、恢复时间均短于对照组（<0.05）。两组不良反应发生率差异无统计学意义，两组均未出现严重不良反应（>0.05）。
结论
低温等离子体消融扁桃体切除术后儿童使用艾司氯胺酮滴鼻剂安全，且可减轻疼痛、缩短恢复时间。
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