Altinkök Çağatay
Department of Chemistry, Faculty of Science and Letters, İstanbul Technical University, İstanbul, Turkey.
Turk J Chem. 2023 Apr 12;47(3):583-590. doi: 10.55730/1300-0527.3562. eCollection 2023.
A novel amphiphilic graft copolymer possessing polypropylene (PP) main chain and poly(oligoethylene glycol methacrylate) (POEGMA) pendant units was synthesized starting from chlorinated polypropylene (PP-Cl), and characterized. PP-Cl produced macroradicals at chlorine bounded carbon atoms by visible light irradiation in the presence of dimanganese decacarbonyl [Mn(CO)] and initiated the free-radical photopolymerization of an acrylate monomer, namely oligoethylene glycol methacrylate (OEGMA). Furthermore, fiber formation ability of PP--POEGMA was tested by electrospinning technique. The chemical structure and some features of the corresponding amphiphilic graft copolymer PP--POEGMA was characterized by implementing spectral (FT-IR, H-NMR), chromatographic (GPC), morphological (SEM), water wettability (WCA), and thermal (TGA) analyses. It was clear from the SEM results that the average diameter of the obtained microfibers decreased with the incorporation of POEGMA segments onto the PP-Cl main chain. Based on WCA measurements, PP--POEGMA was determined as more wettable than PP-Cl due to its hydrophilic POEGMA building blocks. This facile procedure could be utilized to achieve the amphiphilic commercial polymers for potential bioapplications such as drug delivery.
以氯化聚丙烯（PP-Cl）为起始原料，合成并表征了一种具有聚丙烯（PP）主链和聚（甲基丙烯酸寡聚乙二醇酯）（POEGMA）侧基的新型两亲性接枝共聚物。在十羰基二锰[Mn(CO)]存在下，PP-Cl通过可见光照射在与氯相连的碳原子上产生大分子自由基，并引发丙烯酸酯单体即甲基丙烯酸寡聚乙二醇酯（OEGMA）的自由基光聚合反应。此外，采用静电纺丝技术测试了PP-POEGMA的成纤能力。通过光谱（FT-IR、H-NMR）、色谱（GPC）、形态（SEM）、水润湿性（WCA）和热（TGA）分析对相应两亲性接枝共聚物PP-POEGMA的化学结构和一些特性进行了表征。从扫描电子显微镜（SEM）结果可以清楚地看出，随着POEGMA链段接入PP-Cl主链，所得微纤维的平均直径减小。基于水接触角（WCA）测量，由于其亲水性POEGMA结构单元，PP-POEGMA被确定为比PP-Cl更具润湿性。这种简便的方法可用于制备潜在生物应用（如药物递送）的两亲性商业聚合物。
