Pannu Ashok Kumar
Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Turk J Emerg Med. 2023 Jan 9;23(3):139-148. doi: 10.4103/2452-2473.367400. eCollection 2023 Jul-Sep.
Circulatory shock is a common condition that carries high morbidity and mortality. This review aims to update the critical steps in managing common types of shock in adult patients admitted to medical emergency and intensive care units. A literature review was performed by searching PubMed, EMBASE Ovid, and Cochrane Library, using the following search items: ("shock" OR "circulatory shock" OR "septic shock" OR "cardiogenic shock") AND ("management" OR "treatment" OR "resuscitation"). The review emphasizes prompt shock identification with tissue hypoperfusion, knowledge of the underlying pathophysiological mechanism, initial fluid resuscitation with balanced crystalloids, norepinephrine as the preferred vasopressor in septic and profound cardiogenic shock, and tailored intervention addressing specific etiologies. Point-of-care ultrasound may help evaluate an undifferentiated shock and determine fluid responsiveness. The approach to septic shock is improving; however, confirmatory studies are required for many existing (e.g., amount of initial fluids and steroids) and emerging (e.g., angiotensin II) therapies. Knowledge gaps and wide variations persist in managing cardiogenic shock that needs urgent addressing to improve outcomes.
循环休克是一种常见病症,具有高发病率和死亡率。本综述旨在更新对入住医疗急救和重症监护病房的成年患者常见类型休克的关键管理步骤。通过检索PubMed、EMBASE Ovid和Cochrane图书馆进行文献综述,使用以下检索词:(“休克”或“循环休克”或“脓毒症休克”或“心源性休克”)以及(“管理”或“治疗”或“复苏”)。该综述强调通过组织灌注不足迅速识别休克、了解潜在病理生理机制、使用平衡晶体液进行初始液体复苏、在脓毒症和严重心源性休克中使用去甲肾上腺素作为首选血管加压药,以及针对特定病因进行针对性干预。床旁超声有助于评估未分化休克并确定液体反应性。脓毒症休克的治疗方法正在改进;然而,许多现有(如初始液体量和类固醇)和新兴(如血管紧张素II)疗法仍需要验证性研究。在心源性休克的管理方面,知识差距和广泛差异仍然存在,需要紧急解决以改善治疗结果。