Department of Glaucoma, Aravind Eye Hospital, Coimbatore, Tamil Nadu, India.
Indian J Ophthalmol. 2023 Aug;71(8):2962-2966. doi: 10.4103/IJO.IJO_122_23.
To compare the axial length (AL) and corneal diameter between glaucomatous eye (GE) and fellow normal eye (NE) in patients with unilateral congenital glaucoma and to obtain a normative database for ocular growth among Indian children below 3 years of age.
Retrospective longitudinal study. Patients who had a follow-up of 3 years from diagnosis with ocular biometry parameters being recorded at least thrice (once a year) and fellow eye being normal were included. Data collected were age, gender, intraocular pressure (IOP), AL, corneal diameter, optic disc findings, diagnosis, and surgery details.
Eleven patients were analyzed. All GE underwent combined trabeculotomy with trabeculectomy. Mean (SD) baseline IOP, AL, and corneal diameter were 17.1 (6.7) mmHg, 18.9 (1.1) mm and 12 (0.91) mm in GE, and 11.1 (3.8) mmHg, 17.8 (0.44) mm, and 10.5 (0.58) mm in NE, respectively. Increase in AL was 3.1 mm in the first year followed by 0.6 mm in second year and 0.4 mm in third year in GE compared to 2.6, 0.6, and 0.5 mm in NE, respectively. Corneal diameter increased by 1.1 mm in GE in the first year and remained stable thereafter compared to 0.7 mm in first year followed by 0.3 mm in second year and stable thereafter in NE. The percentage of success was 73% at 3 years.
Axial length and corneal diameter were higher in GE than NE at all-time points. With prompt intervention, the growth curve of the GE was made parallel to that of NE.
比较单侧先天性青光眼患者患眼（GE）和对侧正常眼（NE）的眼轴（AL）和角膜直径，为印度 3 岁以下儿童的眼部生长获得一个正常数据库。
回顾性纵向研究。纳入至少随访 3 年且眼部生物测量参数至少记录 3 次（每年一次）、对侧眼正常的患者。收集的数据包括年龄、性别、眼内压（IOP）、AL、角膜直径、视盘检查结果、诊断和手术细节。
分析了 11 例患者。所有 GE 均行小梁切开联合小梁切除术。GE 的基线 IOP、AL 和角膜直径平均值（标准差）分别为 17.1（6.7）mmHg、18.9（1.1）mm 和 12（0.91）mm，NE 分别为 11.1（3.8）mmHg、17.8（0.44）mm 和 10.5（0.58）mm。第一年 AL 增加 3.1mm，第二年增加 0.6mm，第三年增加 0.4mm，而 NE 分别增加 2.6mm、0.6mm 和 0.5mm。第一年 GE 的角膜直径增加 1.1mm，此后保持稳定，而 NE 则分别增加 0.7mm、0.3mm，此后保持稳定。3 年后的成功率为 73%。
在所有时间点，GE 的 AL 和角膜直径均高于 NE。及时干预后，GE 的生长曲线与 NE 的生长曲线平行。
