Trivedi Rupal H, Wilson M Edward
Miles Center for Pediatric Ophthalmology, Storm Eye Institute, Department of Ophthalmology, Medical University of South Carolina (MUSC), Charleston, South Carolina, USA.
Invest Ophthalmol Vis Sci. 2007 Oct;48(10):4671-8. doi: 10.1167/iovs.07-0267.
To report the biometry data of pediatric cataractous eyes (randomly selected single eye in bilateral cases; cataractous eye in unilateral cases) and to compare the biometry data of the unilateral cataractous eye with the data of the corresponding noncataractous fellow eye.
The study was a chart review/analysis of immersion A-scan biometry measurements, excluding traumatic cataract or lens subluxation.
Three hundred ten eyes were examined at surgery. The mean age was 45.30 +/- 48.10 months; globe axial length (AL), 20.52 +/- 2.87 mm; anterior chamber depth (ACD), 3.29 +/- 0.60 mm; and lens thickness (LT), 3.62 +/- 0.86 mm. During the first 6 months of life, AL increased 0.62 mm/mo, 0.19 mm/mo from 6 to 18 months, and 0.01 mm/mo during 18 months to 18 years of age. The girls had shorter ALs than did the boys (P = 0.090), and the African-American subjects had longer ALs than did the Caucasians (P < 0.001). Eyes with unilateral cataract had shorter ALs than those with bilateral cataracts before 60 months of age, but had longer ALs than the eyes with bilateral cataracts after 60 months of age. Eyes of the female subjects had shallower ACDs than those of male subjects (P = 0.026). Eyes with unilateral cataract had shallower ACDs than those of eyes with bilateral cataracts (P = 0.001). In the children >5 years of age, LT was significantly greater in eyes with unilateral cataract than in those with bilateral cataract. AL of the unilateral cataractous eye was significantly shorter than that of the fellow noncataractous eye before 6 months of age (P = 0.001).
This study begins to lay the groundwork for calculating pediatric IOL power in cataractous eyes by using pediatric ocular measurements.
报告小儿白内障眼(双侧病例中随机选择的单眼;单侧病例中的白内障眼)的生物测量数据,并将单侧白内障眼的生物测量数据与相应的对侧非白内障眼的数据进行比较。
本研究是对浸没式A超生物测量结果的图表回顾/分析,排除外伤性白内障或晶状体半脱位。
手术时检查了310只眼。平均年龄为45.30±48.10个月;眼轴长度(AL)为20.52±2.87mm;前房深度(ACD)为3.29±0.60mm;晶状体厚度(LT)为3.62±0.86mm。在出生后的前6个月,AL每月增加0.62mm,6至18个月时每月增加0.19mm,18个月至18岁时每月增加0.01mm。女孩的AL比男孩短(P = 0.090),非裔美国受试者的AL比白种人长(P < 0.001)。60个月之前,单侧白内障眼的AL比双侧白内障眼短,但60个月之后,单侧白内障眼的AL比双侧白内障眼长。女性受试者的ACD比男性受试者浅(P = 0.026)。单侧白内障眼的ACD比双侧白内障眼浅(P = 0.001)。在5岁以上的儿童中,单侧白内障眼的LT明显大于双侧白内障眼。6个月之前,单侧白内障眼的AL明显短于对侧非白内障眼(P = 0.001)。
本研究开始为利用小儿眼部测量结果计算白内障眼中的小儿人工晶状体度数奠定基础。