基于智能手机的立体镜系统治疗虚拟现实（VR）成人弱视的初步非随机试验。

A pilot non-randomized trial of smartphone-based anaglyph system for treatment of adult amblyopia through VR (Virtual Reality).

机构信息

Department of Optometry and Vision Sciences, C L Gupta Eye Institute, Ramganga Vihar Phase - II (Extn), Moradabad, Uttar Pradesh, India.

Department of Paediatric Ophthalmology and Strabismus, C L Gupta Eye Institute, Ramganga Vihar Phase - II (Extn), Moradabad, Uttar Pradesh, India.

出版信息

Indian J Ophthalmol. 2023 Aug;71(8):3001-3004. doi: 10.4103/IJO.IJO_3225_22.

DOI:10.4103/IJO.IJO_3225_22

PMID:37530272

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10538819/

Abstract

PURPOSE

To evaluate the effectiveness of amblyopia treatment through a smartphone-based anaglyph system by virtual reality (VR) in adult patients.

METHODS

A total of 10 subjects diagnosed with anisometropic amblyopia were enrolled during the study period. Best Corrected Visual Acuity (BCVA), stereoacuity, and contrast acuity were evaluated during three visits (at presentation, 3 months and 6 months) of smartphone-based anaglyph video run in the VR mode. All the amblyogenic factors including stereopsis, color vision, and contrast acuity were compared using Friedman two-way analysis of variance. Statistical significance was considered if P < 0.05.

RESULTS

Mean BCVA in amblyopic eye improved significantly from a logMAR value of 0.73 ± 0.64 before Virtual reality vision therapy (VRVT) to a post-training VRVT value of 0.48 ± 0.44 (P < 0.01). Mean stereoacuity changed from a value of 560.00 ± 301.58 before VRVT to a value of 263.00 ± 143.58 seconds of arc after training (VRVT) (P < 0.01). Mean accommodation changes from a value of 15.00 ± 7.40 before training or VRVT to value of 12.60 ± 6.10 cm after training (P < 0.01). Mean contrast acuity changes from a value of 1.21 ± 0.72 at presentation to a value of 1.52 ± 0.49 log unit after VRVT.

CONCLUSION

A smartphone-based anaglyph system using VR vision therapy appears to be an effective treatment option for amblyopia in adults.

摘要

目的

通过基于智能手机的虚拟现实（VR）立体镜系统评估成人弱视患者的治疗效果。

方法

本研究共纳入 10 名被诊断为屈光不正性弱视的患者。在基于智能手机的立体镜视频 VR 模式下进行三次就诊（就诊时、3 个月和 6 个月），评估最佳矫正视力（BCVA）、立体视锐度和对比敏感度。使用 Friedman 双向方差分析比较所有致弱视因素，包括立体视、色觉和对比敏感度。如果 P<0.05，则认为具有统计学意义。

结果

弱视眼的平均 BCVA 从 VRVT 前的 logMAR 值 0.73±0.64 显著提高到训练后的 VRVT 值 0.48±0.44（P<0.01）。平均立体视锐度从 VRVT 前的 560.00±301.58 秒变为训练后的 263.00±143.58 秒（P<0.01）。平均调节从训练或 VRVT 前的 15.00±7.40 变为训练后的 12.60±6.10 cm（P<0.01）。平均对比敏感度从就诊时的 1.21±0.72 变为 VRVT 后的 1.52±0.49 对数单位。