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印度北部一家三级护理中心的青光眼和非青光眼患者的视觉相关生活质量(VRQoL)比较研究。

A comparative study of vision-related quality of life (VRQoL) among glaucoma and nonglaucoma patients at a tertiary care center of North India.

机构信息

Department of Ophthalmology, All India Institute of Medical Sciences, Gorakhpur, Uttar Pradesh, India.

Department of Community Medicine and Family Medicine and, All India Institute of Medical Sciences, Gorakhpur, Uttar Pradesh, India.

出版信息

Indian J Ophthalmol. 2023 Aug;71(8):3010-3015. doi: 10.4103/IJO.IJO_56_23.

Abstract

PURPOSE

Glaucoma influences vision-related quality of life (VRQoL) of an individual in various ways. There are very limited studies on the Indian population and the northern part of India. Therefore, we conducted the present study to evaluate VRQoL in glaucoma patients as well as the association between the severity of glaucoma and VRQoL.

METHODS

An institution-based, cross-sectional, analytical study was conducted from August 2022 to October 2022 involving 190 participants (95 glaucoma patients and 95 controls). The glaucoma quality of life-15 (GQL-15) questionnaire was explained in their vernacular language by the interviewer. The scoring was given according to the validated scoring algorithm for the questionnaire.

RESULTS

Mean GQL score in the control group was 19.66 ± 5.5 and in glaucoma cases was 32.8 ± 10.2, whereas the mean score of mild glaucoma cases was 22.3 ± 4.83, moderate glaucoma cases was 36.3 ± 4.09, and severe glaucoma cases was 47.24 ± 3.03. Therefore, as the severity of glaucoma increases, the GQL score also increases, indicating poorer quality of life. Visual field loss was strongly positively correlated (correlation coefficient = 0.759, P < 0.01) with the GQL-15 score, while a weaker positive correlation was found with best corrected visual acuity (BCVA), cup disc ratio, and duration of treatment.

CONCLUSION

Besides controlling or reducing intraocular pressure (IOP) to the target level, the goal of glaucoma treatment should be to provide an individual with good functional vision to maintain an acceptable quality of life. It would also help in providing patients with the best possible treatment, not only in terms of good vision but also in maintaining or improving their overall quality of life.

摘要

目的

青光眼以多种方式影响个体的视觉相关生活质量(VRQoL)。针对印度人群和印度北部地区的研究非常有限。因此,我们进行了本研究,以评估青光眼患者的 VRQoL 以及青光眼严重程度与 VRQoL 之间的关联。

方法

本研究为 2022 年 8 月至 2022 年 10 月进行的一项基于机构的、横断面、分析性研究,共纳入 190 名参与者(95 名青光眼患者和 95 名对照)。由访谈员用当地语言解释青光眼生活质量-15 (GQL-15)问卷。根据问卷的验证评分算法进行评分。

结果

对照组的平均 GQL 得分为 19.66±5.5,青光眼患者为 32.8±10.2,而轻度青光眼患者的平均得分为 22.3±4.83,中度青光眼患者为 36.3±4.09,严重青光眼患者为 47.24±3.03。因此,随着青光眼严重程度的增加,GQL 评分也增加,表明生活质量更差。视野丧失与 GQL-15 评分呈强烈正相关(相关系数=0.759,P<0.01),与最佳矫正视力(BCVA)、杯盘比和治疗持续时间呈较弱正相关。

结论

除了将眼内压(IOP)控制或降低到目标水平外,青光眼治疗的目标还应该是为个体提供良好的功能性视力,以维持可接受的生活质量。这还有助于为患者提供尽可能好的治疗,不仅在良好视力方面,而且在维持或改善整体生活质量方面。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3660/10538840/668a6f54b59a/IJO-71-3010-g001.jpg

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