Kennard Beth D, Hughes Jennifer L, Minhajuddin Abu, Slater Holli, Blader Joseph C, Mayes Taryn L, Kirk Claire, Wakefield Sarah M, Trivedi Madhukar H
The Peter O'Donnell Jr. Brain Institute and the Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Peter O'Donnell Jr. School of Public Health, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Suicide Life Threat Behav. 2023 Oct;53(5):748-763. doi: 10.1111/sltb.12980. Epub 2023 Aug 2.
Suicidality in youth is a serious public health problem. The Texas Youth Depression and Suicide Research Network (TX-YDSRN) was initiated in 2020 to create a research registry for youth with depression and/or suicidality in Texas. This report presents baseline clinical/demographic characteristics of the first 1000 participants, focusing on suicidal thoughts and behaviors.
The registry includes 8-20-year-old youth receiving treatment for depression, or who screen positive for depression and/or suicidal ideation/behavior. Baseline data include diagnosis, depression/anxiety severity, suicidal ideation/behavior, trauma history, and measures of resilience.
We present baseline data on the first 1000 participants. Most (79.6%) of the sample had a primary depressive disorder. The sample had moderate to severe depression (Patient Health Questionnaire for Adolescents, PHQ-A; 12.9 ± 6.4) and anxiety (Generalized Anxiety Disorder, GAD-7; 11.3 ± 5.9). Nearly half reported ≥1 lifetime suicide attempts and 90% reported lifetime or current suicidal ideation. Participants with past/current suicidality (attempts and/or ideation) had greater illness severity (depression, anxiety, and suicidal thoughts/behaviors), lower resilience, and higher rates of trauma exposure than those without suicidality.
Baseline data indicate moderate levels of depression, anxiety, and suicidality and their correlates in this cohort. Future reports will determine trajectories of outcomes and predictors, moderators, and social determinants related to these outcomes.
青少年自杀倾向是一个严重的公共卫生问题。德克萨斯青少年抑郁与自杀研究网络（TX - YDSRN）于2020年启动，旨在为德克萨斯州患有抑郁症和/或有自杀倾向的青少年创建一个研究登记册。本报告呈现了前1000名参与者的基线临床/人口统计学特征，重点关注自杀念头和行为。
该登记册纳入了年龄在8至20岁、正在接受抑郁症治疗或抑郁症及/或自杀意念/行为筛查呈阳性的青少年。基线数据包括诊断结果、抑郁/焦虑严重程度、自杀意念/行为、创伤史以及心理韧性指标。
我们展示了前1000名参与者的基线数据。样本中的大多数（79.6%）患有原发性抑郁症。样本的抑郁程度为中度至重度（青少年患者健康问卷，PHQ - A；12.9 ± 6.4），焦虑程度为中度至重度（广泛性焦虑障碍，GAD - 7；11.3 ± 5.9）。近一半的人报告有≥1次终身自杀未遂经历，90%的人报告有终身或当前自杀意念。与无自杀倾向的参与者相比，有过去/当前自杀倾向（未遂和/或意念）的参与者疾病严重程度更高（抑郁、焦虑和自杀念头/行为），心理韧性更低，创伤暴露率更高。
基线数据表明该队列中抑郁、焦虑和自杀倾向及其相关因素处于中等水平。未来的报告将确定与这些结果相关的结局轨迹以及预测因素、调节因素和社会决定因素。
