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游离葡萄糖传感器缺陷致糖尿病酮症酸中毒:1 例报告。

Diabetic ketoacidosis due to a sensor defect of FreeStyle Libre: A case report.

机构信息

Department of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan.

出版信息

J Diabetes Investig. 2023 Nov;14(11):1321-1324. doi: 10.1111/jdi.14065. Epub 2023 Aug 2.

DOI:10.1111/jdi.14065
PMID:37530563
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10583651/
Abstract

The FreeStyle Libre Flash Glucose Monitoring System allows users to obtain sensor glucose values by scanning with the reader or their mobile phone. We report a case of a 59-year-old man with type 1 diabetes mellitus who developed diabetic ketoacidosis due to a sensor defect. After replacing the sensor with a new one, the glucose value shown in the device was much lower than usual, which made him consider that he was hypoglycemic. Accordingly, he reduced his insulin dose and eventually developed diabetic ketoacidosis. He was unaware of the discrepancy due to the lack of self-monitoring of his blood glucose, although he was educated to do. In sum, glucose monitoring with the FreeStyle Libre is helpful; however, it is necessary to remind the patient that a sensor defect leading to a severe complication frequently happens.

摘要

FreeStyle Libre 瞬感葡萄糖监测系统允许用户通过扫描读取器或移动电话来获得传感器葡萄糖值。我们报告了一例 59 岁的 1 型糖尿病患者,由于传感器故障导致糖尿病酮症酸中毒。更换新传感器后,设备显示的血糖值远低于正常水平,这使他认为自己出现了低血糖。因此,他减少了胰岛素剂量,最终导致糖尿病酮症酸中毒。尽管他接受过相关教育,但由于缺乏自我血糖监测,他没有意识到这种差异。总之,使用 FreeStyle Libre 进行血糖监测是有帮助的;然而,有必要提醒患者,传感器故障会经常导致严重并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5991/10583651/51bb00aa9a6b/JDI-14-1321-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5991/10583651/fee0bff7ce10/JDI-14-1321-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5991/10583651/c581f7c581f4/JDI-14-1321-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5991/10583651/51bb00aa9a6b/JDI-14-1321-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5991/10583651/fee0bff7ce10/JDI-14-1321-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5991/10583651/c581f7c581f4/JDI-14-1321-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5991/10583651/51bb00aa9a6b/JDI-14-1321-g003.jpg

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本文引用的文献

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Diabetes Technol Ther. 2023 Jan;25(1):20-30. doi: 10.1089/dia.2022.0271. Epub 2022 Nov 24.
2
Effectiveness of continuous glucose monitoring in maintaining glycaemic control among people with type 1 diabetes mellitus: a systematic review of randomised controlled trials and meta-analysis.持续葡萄糖监测对1型糖尿病患者维持血糖控制的有效性:随机对照试验的系统评价和荟萃分析
Diabetologia. 2022 Apr;65(4):604-619. doi: 10.1007/s00125-021-05648-4. Epub 2022 Feb 9.
3
Effects of real-time continuous glucose monitoring in type 1 diabetes: a meta-analysis of randomized controlled trials.实时连续血糖监测在 1 型糖尿病中的作用:一项随机对照试验的荟萃分析。
Acta Diabetol. 2021 Apr;58(4):401-410. doi: 10.1007/s00592-020-01589-3. Epub 2020 Aug 13.
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Effects of Continuous Glucose Monitoring on Metrics of Glycemic Control in Diabetes: A Systematic Review With Meta-analysis of Randomized Controlled Trials.连续血糖监测对糖尿病血糖控制指标的影响:一项随机对照试验的系统评价和荟萃分析。
Diabetes Care. 2020 May;43(5):1146-1156. doi: 10.2337/dc19-1459.
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Clinical Recommendations for the Use of the Ambulatory Glucose Profile in Diabetes Care.临床推荐在糖尿病护理中使用动态血糖监测。
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