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Multiomics-based study of amniotic fluid small extracellular vesicles identified Moesin as a biomarker for antenatal hydronephrosis.

作者信息

Li Jingzhi, Fu Ying, Liu Qiaoshu, Shen Kuifang, Yao Ruojin, Fu Yimei, Lu Yang, Xie Mingkun, Jian Wenyan, Guo Ming, Dai Lei, Zhang Weishe

机构信息

Department of Obstetrics, Xiangya Hospital Central South University, Changsha, China.

Hunan Engineering Research Center of Early Life Development and Disease Prevention, Changsha, China.

出版信息

Clin Transl Med. 2023 Aug;13(8):e1360. doi: 10.1002/ctm2.1360.

DOI:10.1002/ctm2.1360
PMID:37531302
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10395771/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c72/10395771/104b618d8478/CTM2-13-e1360-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c72/10395771/35b41810d686/CTM2-13-e1360-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c72/10395771/1c12fd309c35/CTM2-13-e1360-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c72/10395771/00c48408efd1/CTM2-13-e1360-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c72/10395771/104b618d8478/CTM2-13-e1360-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c72/10395771/35b41810d686/CTM2-13-e1360-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c72/10395771/1c12fd309c35/CTM2-13-e1360-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c72/10395771/00c48408efd1/CTM2-13-e1360-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c72/10395771/104b618d8478/CTM2-13-e1360-g004.jpg

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Multiomics-based study of amniotic fluid small extracellular vesicles identified Moesin as a biomarker for antenatal hydronephrosis.基于多组学的羊水小细胞外囊泡研究确定埃兹蛋白为产前肾积水的生物标志物。
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引用本文的文献

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Extracellular vesicles: their challenges and benefits as potential biomarkers for musculoskeletal disorders.细胞外囊泡:作为肌肉骨骼疾病潜在生物标志物面临的挑战与益处
J Int Med Res. 2025 Feb;53(2):3000605251317476. doi: 10.1177/03000605251317476.
3
[Differential expression profile of miRNAs in maternal amniotic fluid exosomes in fetuses with isolated ventriculomegaly].

本文引用的文献

1
Combination of Size-Exclusion Chromatography and Ultracentrifugation Improves the Proteomic Profiling of Plasma-Derived Small Extracellular Vesicles.尺寸排阻色谱法与超速离心法相结合可改善血浆来源的小细胞外囊泡的蛋白质组分析。
Biol Proced Online. 2020 Jun 23;22:12. doi: 10.1186/s12575-020-00125-5. eCollection 2020.
2
Management of antenatal hydronephrosis.产前肾积水的处理。
Pediatr Nephrol. 2020 Dec;35(12):2231-2239. doi: 10.1007/s00467-019-04420-6. Epub 2019 Dec 6.
3
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines.
[孤立性脑室扩大胎儿母体羊水外泌体中微小RNA的差异表达谱]
Nan Fang Yi Ke Da Xue Xue Bao. 2024 Nov 20;44(11):2256-2264. doi: 10.12122/j.issn.1673-4254.2024.11.24.
4
Extracellular vesicles as carriers of mRNA: Opportunities and challenges in diagnosis and treatment.细胞外囊泡作为 mRNA 的载体:在诊断和治疗中的机遇与挑战。
Theranostics. 2024 Mar 11;14(5):2265-2289. doi: 10.7150/thno.93115. eCollection 2024.
细胞外囊泡研究的最低限度信息2018(MISEV2018):国际细胞外囊泡协会的立场声明及MISEV2014指南的更新
J Extracell Vesicles. 2018 Nov 23;7(1):1535750. doi: 10.1080/20013078.2018.1535750. eCollection 2018.
4
Ultrasound Markers in Fetal Hydronephrosis to Predict Postnatal Surgery.胎儿肾积水的超声标志物预测产后手术。
Ultraschall Med. 2020 Jun;41(3):278-285. doi: 10.1055/a-0591-3303. Epub 2018 Jul 5.
5
Multidisciplinary consensus on the classification of antenatal and postnatal urinary tract dilation (UTD classification system).产前和产后泌尿道扩张分类的多学科共识(UTD分类系统)。
Pediatr Radiol. 2015 Jun;45(6):787-9. doi: 10.1007/s00247-015-3305-0. Epub 2015 Mar 13.
6
Urinary biomarkers in hydronephrosis.肾积水的尿液生物标志物
Dan Med J. 2013 Feb;60(2):B4582.
7
The Society for Fetal Urology consensus statement on the evaluation and management of antenatal hydronephrosis.胎儿泌尿外科学会关于产前肾积水的评估和管理的共识声明。
J Pediatr Urol. 2010 Jun;6(3):212-31. doi: 10.1016/j.jpurol.2010.02.205. Epub 2010 Apr 15.
8
Phosphoproteomic study of human tubular epithelial cell in response to transforming growth factor-beta-1-induced epithelial-to-mesenchymal transition.人肾小管上皮细胞在转化生长因子-β1诱导上皮-间质转化中的磷酸化蛋白质组学研究。
Am J Nephrol. 2010;31(1):24-35. doi: 10.1159/000253865. Epub 2009 Oct 28.
9
Antenatal hydronephrosis.产前肾积水
Curr Urol Rep. 2009 Mar;10(2):126-33. doi: 10.1007/s11934-009-0023-x.
10
Antenatal hydronephrosis: differential diagnosis, evaluation, and treatment options.产前肾积水:鉴别诊断、评估及治疗方案
ScientificWorldJournal. 2006 Mar 5;6:2345-65. doi: 10.1100/tsw.2006.366.