增强子动态：解析转录爆发的机制。
Enhancer dynamics: Unraveling the mechanism of transcriptional bursting.
机构信息
Laboratory of Transcription Dynamics, Research Center for Biological Visualization, Institute for Quantitative Biosciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0032, Japan.
Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0032, Japan.
出版信息
Sci Adv. 2023 Aug 2;9(31):eadj3366. doi: 10.1126/sciadv.adj3366.
Abstract
Transcriptional bursting is a prevalent feature of gene expression. The transient assembly of transcription factor clusters at regulatory DNAs is critical to control bursting dynamics.
摘要
转录爆发是基因表达的一个普遍特征。转录因子簇在调控 DNA 处的短暂组装对于控制爆发动力学至关重要。
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