Huber S J, Shuttleworth E C, Paulson G W
Arch Neurol. 1986 Oct;43(10):987-90. doi: 10.1001/archneur.1986.00520100009006.
Estimates of the prevalence of dementia in patients with Parkinson's disease (PD) vary considerably. Dementia in PD has been linked to a visuospatial disturbance, impairment of memory, and depression. Previous research suggests that visuospatial deficits and depression do not vary with severity of intellectual decline and thus are not useful measures to distinguish demented from nondemented patients. We examined immediate, recent, and remote memory in patients with PD and found that unlike visuospatial performance and depression, a qualitatively distinct pattern emerged, which did vary with severity of intellectual decline.
帕金森病(PD)患者痴呆症患病率的估计差异很大。帕金森病中的痴呆症与视觉空间障碍、记忆力减退和抑郁症有关。先前的研究表明,视觉空间缺陷和抑郁症不会随着智力衰退的严重程度而变化,因此不是区分痴呆患者和非痴呆患者的有用指标。我们研究了帕金森病患者的即刻记忆、近期记忆和远期记忆,发现与视觉空间表现和抑郁症不同,出现了一种性质上截然不同的模式,这种模式确实会随着智力衰退的严重程度而变化。